Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)

Cat. # Quantity Price Lead time
3662-5mg 5 mg $129 in stock
3662-25mg 25 mg $240 in stock
3662-100mg 100 mg $630 in stock
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The tetraacetylated N-Azidoacetyl-glucosamine (Ac4GlcNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GlcNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylglucosamine (GlcNAc).

The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.

The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.

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DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

General properties

Appearance: white solid
Molecular weight: 430.37
CAS number: 98924-81-3
Molecular formula: C16H22N4O10
Solubility: DMSO, DMF, DCM, THF, Chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
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