2′-Deoxyadenosine-d2
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 4892-1mg | 1 mg |
$44
|
12 days |
2′-Deoxyadenosine-(ribose-5,5-d2) is a deuterated form of the nucleoside 2'-deoxyadenosine and is intended for use as an internal standard for the quantification of deoxyadenosine by LC-MS.
Deoxyadenosine is a nucleoside that is converted to deoxyinosine by the enzyme adenosine deaminase (ADA). Accumulation of deoxyadenosine in the abscence of ADA exhibits higher toxicity in lymphoid cells and can inhibit the growth of kinase-deficient cells by inactivating S-adenosylhomocysteine hydrolase (AdoHcyase) and disrupting methylation processes. The triphosphorylated forms of deoxyadenosine analogs are potent inhibitors of ribonucleotide reductase (RNR).
General properties
| Appearance: | white powder |
| Molecular weight: | 253.26 |
| Molecular formula: | C10H11D2N5O3 |
| Solubility: | in water |
| Quality control: | NMR 1H and HPLC-MS (95+ %, D: 98+ %) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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