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Fluorescent dyes and quenchers

Fluorescent dyes and quenchers / product groups & items in this category
Fluorescent dyes and quenchers for the labeling of biomolecules.

Activated esters

Fluorescent dye NHS and STP esters are amine-reactive dyes with an activated ester group.
Group tags Near infrared (NIR) imaging, DusQ 21, AF 488, Crosslinking, Cyanine3B, AF 568, BDP® R6G, sulfo-Cyanine3.5, sulfo-Cyanine5.5, NHS esters, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, BDP® 558/568, Cyanine5, DusQ 1, BDP® 650/665, AF 594, FAM (Fluorescein), AF 555, BDP® 576/589, BDP® FL, AF 532, BDP® TMR, DusQ 2, Cyanine3.5, Cyanine7.5, BDP® 581/591, DusQ 3, ROX (Rhodamine X, Rhodamine 101), Cyanine3, AF 430, Pyrene, JOE, TAMRA (TMR, Tetramethylrhodamine), Alkynes, R6G, Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, BDP® 564/570, AF 647, BDP® 630/650, BDP® TR, ATT 550, TFP esters, Click chemistry, HEX (Hexachlorofluorescein), TR, Super-resolution imaging, sulfo-Cyanine5, AF 343 (Coumarin), Protein labeling, AMCA
  • (5,6)-FAM diacetate NHS ester
    Amine-reactive fluorescein (FAM) derivative, a mixture of 5- and 6-isomers. The reagent becomes brightly green fluorescent once it is hydrolyzed while diffusing into cells. A fluorescent tracer.
  • AF 343 (Coumarin)-X-NHS ester
    AF 343 (Coumarin) is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.
  • AF 430 NHS ester
    AF 430 is a hydrophilic coumarin dye with emission in the green-yellow range. The NHS ester is used for the labeling of amine groups.
  • AF 488 NHS ester
    AF 488 NHS ester, a bright, photostable, and hydrophilic fluorescent dye for the green channel.
  • AF 488 TFP ester
    Tetrafluorophenyl ester of green fluorescent dye AF 488 for labeling amino groups in proteins, peptides, and modified oligonucleotides.
  • AF 532 NHS ester
    NHS-ester of AF 532 dye for protein, peptide, and modified oligonucleotide labeling via reaction with amino groups.
  • AF 555 NHS ester
    AF 555 NHS ester, a bright, photostable, and hydrophilic fluorescent dye for the yellow channel.
  • AF 568 NHS ester
    AF 568 derivative for labeling proteins and other high- and low-molecular weight ligands with free amines.
  • AF 594 NHS ester
    Red-fluorescent NHS-ester of AF 594 dye for labeling proteins, peptides, antibodies, and any molecules containing an -NH2 group. Pure 5-isomer
  • AF 647 NHS ester
    Bright, water-soluble succinimide ester of AF 647 dye for protein and antibody labeling.
  • AMCA NHS ester
    NHS-ester of AMCA dye for protein, peptide, and modified oligonucleotide labeling via reaction with amino groups. AMCA is one of the brightest blue fluorescent dyes with large Stoke's shift and high resistance to photobleaching.
  • ATT 550 NHS ester
    Water-soluble ATT 550 succinimidyl ester for labeling various amine-containing molecules in the aqueous phase.
  • BDP 564/570 NHS ester
    Lypohilic borodipyrromethene dye with orange emission for the labeling of primary and secondary amine groups.
  • BDPep 630/650 NHS ester
    Dicyano BDP 630/650 is a far-red fluorescent dye from the boron dipyrromethene (BDP) family, known for its high brightness and exceptional photostability. Its remarkable stability in strong acidic TFA media makes it particularly suitable for solid-phase peptide synthesis (SPPS). BDPep 630/650 NHS ester can be used for effective cell sorting and phenotyping.
  • BDPep FL NHS ester
    BDP FL analog derivative suitable for solid phase synthesis SPPS.
  • BDP® 558/568 NHS ester
    BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.
  • BDP® 576/589 NHS ester
    BDP 576/589 NHS ester is a bright hydrophobic dye with emission in the orange spectrum range. It can be used in fluorescence anisotropy assays.
  • BDP® 581/591 NHS ester
    NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.
  • BDP® 630/650-X-NHS ester
    BDP 630/650 is a borondipyrromethene fluorophore tuned to Cyanine5 excitation and emission channels. The dye is bright and highly photostable. It is useful for fluorescence polarization assays. This is an amine-reactive NHS ester derivative.
  • BDP® 650/665-X-NHS ester
    Amine-reactive of BDP 650/665, a borondipyrromethene dye for Cy5 channel possessing a high molar extinction coefficient and a good emission quantum yield.
  • BDP® FL NHS ester
    Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.
  • BDP® R6G NHS ester
    BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.
  • BDP® TMR NHS ester
    Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.
  • BDP® TMR-X-NHS ester
    Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays. This compound contains an aminohexanoic acid (C6) linker between the dye and the functional group.
  • BDP® TR-X-NHS ester
    BDP TR-X-NHS ester is a derivative of BDP TR containing a long linker based on aminohexanoic acid (C6). The dye has absorption and emission close to ROX. The NHS ester function can be used to conjugate proteins and peptides.
  • Cyanine3 NHS ester
    Amine-reactive Cyanine3 dye NHS ester for the labeling of amino-groups.
  • Cyanine3.5 NHS ester
    Cyanine3.5 dye NHS ester derivative the labeling of amino-groups in biomolecules.
  • Cyanine3B NHS ester
    Cyanine3B NHS ester is a reactive dye with significantly increased fluorescence quantum yield and photostability for the specific labeling of amino-groups in biomolecules.
  • Cyanine5 NHS ester
    Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.
  • Cyanine5.5 NHS ester
    Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.
  • Cyanine7 NHS ester
    Amine reactive NHS ester of near infrared fluorescent dye, an improved analog of Cy7®.
  • Cyanine7.5 NHS ester
    Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5 .
  • DusQ 1 NHS ester
    Functionalized DusQ 1 quencher derivative with quenching range from 480 - 580 nm for labeling of amine-containing molecules.
  • DusQ 2 NHS ester
    DusQ 2 dark quencher with a quenching range from 560 - 670 nm with primary amine reactivity for synthesis of FRET probes. This NHS ester can be coupled to various molecules bearing amino groups.
  • DusQ 21 NHS ester
    Amino-reactive NHS ester with quencher for the conjugation with amines-containing molecules, DusQ 21 quenching range 590 - 720 nm.
  • DusQ 3 NHS ester
    Amino-reactive NHS ester for the labeling with far-red quencher DusQ 3.
  • FAM NHS ester, 6-isomer
    Activated N-hydroxysuccinimide ester of fluorescein (FAM), pure 6-isomer.
  • FAM isothiocyanate (FITC), 5- and 6-isomers
    An isothiocyanate derivative of fluorescein for labeling of antibodies and other biomolecules. Mix of 5- and 6-isomers.
  • HEX NHS ester, 6-isomer
    NHS-ester of HEX dye for proteins, peptides, and modified oligonucleotides labeling via reaction with amino groups.
  • JOE NHS ester, 5-isomer
    JOE is a fluorescent dye with emission in the yellow part of the spectrum. This derivative is an activated NHS ester for conjugation with amines.
  • Pyrenebutyric acid NHS ester
    Pyrene NHS ester for the labeling of biomolecules with pyrene residue. Pyrene is a fluorescent proximity probe which forms excimers, and it is also an anchor group for graphite immobilization.
  • R6G NHS ester, 5-isomer
    R6G (rhodamine 6G) NHS ester, pure 5-isomer. This dye is often used for the labeling of oligonucleotides for qPCR.
  • ROX NHS ester, 5-isomer
    Activated NHS ester of ROX (rhodamine X or rhodamine 101), pure 5-isomer, for the labeling of amine groups of biomolecules.
  • ROX NHS ester, 6-isomer
    Pure 6-isomer of ROX (Rhodamine X, R101) NHS-ester for amine labeling.
  • TAMRA NHS ester, 5-isomer
    Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides. Pure 5-isomer.
  • TAMRA NHS ester, 6-isomer
    NHS-ester of TAMRA dye for proteins, peptides, and modified oligonucleotides labeling via reaction with amino groups. Pure 6-isomer.
  • TR-X-NHS ester, 5-isomer
    TR is a red-emitting fluorescent dye based on sulforhodamine scaffold, an amine-reactive NHS ester.
  • Thiazole Orange NHS ester
    Thiazole Orange NHS ester for labeling biomolecules (peptides, proteins, amino-DNA, etc.). Thiazole orange is a cyanine dye that is essentially dark in solution but has a bright fluorescence in double-stranded DNA and RNA.
  • sulfo-Cyanine3 NHS ester
    Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.
  • sulfo-Cyanine3.5 NHS ester
    Amine-reactive activated ester of water-soluble, sulfonated sulfo-Cyanine3.5 dye.
  • sulfo-Cyanine5 NHS ester
    Water-soluble sulfo-Cyanine5 succinimidyl ester for labeling various amine-containing molecules in the aqueous phase.
  • sulfo-Cyanine5 alkyne NHS ester
    Bifunctional derivative of sulfo-Cyanine5 dye containing reactive groups of terminal alkyne and NHS ester.
  • sulfo-Cyanine5 bis-NHS ester
    Water soluble amine reactive Cyanine5 dye with two NHS ester groups.
  • sulfo-Cyanine5.5 NHS ester
    Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.
  • sulfo-Cyanine7 NHS ester
    sulfo-Cyanine7 NHS ester is a water-soluble, near-infrared, amine-reactive dye.
  • sulfo-Cyanine7 bis-NHS ester
    sulfo-Cyanine7 bis-NHS ester is a bifunctional derivative of water-soluble near-infrared sulfo-Cyanine7. It contains two activated ester functional groups.
  • sulfo-Cyanine7.5 NHS ester
    A water-soluble near-infrared emitting dye for in vivo imaging applications. sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield and a linker arm.

Azides

Fluorescent dye azides for сlick сhemistry labeling.
Group tags Near infrared (NIR) imaging, AF 488, Crosslinking, Cyanine3B, AF 568, PEP (Phenylethynyl-pyrene), BDP® R6G, ATT 565, sulfo-Cyanine3.5, sulfo-Cyanine5.5, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, BDP® 558/568, Cyanine5, TET (Tetrachlorofluorescein), BDP® 650/665, AF 594, FAM (Fluorescein), AF 555, BDP® 576/589, BDP® FL, BDP® TMR, Cyanine3.5, Cyanine7.5, BDP® 581/591, DusQ 3, ROX (Rhodamine X, Rhodamine 101), Cyanine3, Azides, AF 430, Pyrene, JOE, TAMRA (TMR, Tetramethylrhodamine), ATT 594, Hydrazides, R6G, Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, AF 647, VIC, BDP® 630/650, BDP® TR, ATT 550, SIMA (Dichloro-diphenyl-fluorescein), Click chemistry, HEX (Hexachlorofluorescein), TR, Super-resolution imaging, sulfo-Cyanine5, AF 343 (Coumarin), AMCA
  • AF 343 (Coumarin)-X-azide
    AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.
  • AF 384 (PEP) azide
    PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for click-chemistry labeling.
  • AF 430 azide
    Azide derivative of AF 430 for labeling and detecting alkyne-containing biomolecules via сlick reaction.
  • AF 488 azide
    AF 488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.
  • AF 555 azide
    Azide derivative of yellow fluorescent dye AF 555 for сlick сhemistry.
  • AF 568 azide
    Azide derivative of water-soluble AF 568 dye for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects. Pure 6-isomer.
  • AF 594 azide
    Azide derivative of water-soluble red-fluorescent dye AF 594 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects. Pure 6-isomer.
  • AF 647 azide
    Bright and photostable azide AF 647 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
  • AMCA azide
    Azide derivative of AMCA fluorescent dye for сlick сhemistry. AMCA is one of the brightest blue fluorescent dyes with large Stoke's shift and high resistance to photobleaching.
  • ATT 550 azide
    Azide derivative of water-soluble yellow-fluorescent dye ATT 550 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
  • ATT 565 azide
    Azide derivative of water-soluble orange-fluorescent dye ATT 565 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects. Pure 6-isomer.
  • ATT 594 azide
    Azide derivative of water-soluble red fluorescent dye ATT 594 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
  • ATT 633 azide
    Azide derivative of water-soluble far-red fluorescent dye ATT 633 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.
  • Azide-PEG4-hydrazide
    A bifunctional reagent containing the azide group and hydrazide function. It reacts with aldehydes and ketones. The azide group can then be coupled with various alkynes via CuAAC reaction.
  • BDP® 558/568 azide
    BDP 558/568 is a borondipyrromethene fluorophore with absorption and emission spectra close to Cyanine3. This is an azide derivative for сlick chemistry.
  • BDP® 576/589 azide
    Azide derivative of BDP 576/589 dye for labeling and detecting alkyne-containing biomolecules via сlick reaction.
  • BDP® 581/591 azide
    BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for сlick chemistry.
  • BDP® 630/650 azide
    BDP 630/650 is a bright borondipyrromethene-based fluorophore for the far red area of the spectrum. It possesses a high extinction coefficient and quantum yield. This is an azide for сlick chemistry labeling.
  • BDP® 650/665 azide
    BDP 650/665 is a red-emitting borondipyrromethene dye. This azide derivative can be conjugated with alkynes and cycloalkynes.
  • BDP® FL azide
    BDP FL is a bright and photostable borondipyrromethene dye for the fluorescein channel. This is a dye azide for сlick сhemistry.
  • BDP® R6G azide
    BDP R6G is a high performance borondipyrromethene fluorophore which is tuned to match excitation and emission channels of R6G dye.
  • BDP® TMR azide
    Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.
  • BDP® TR azide
    BDP TR is a red-emitting fluorophore for the ROX channel. This is an azide for copper-catalyzed and copper-free сlick chemistry conjugation.
  • Cholesterol-PEG4-azide
    Cholesterol derivative with azide group for сlick chemistry conjugation.
  • Cyanine3 azide
    Azide derivative of Cyanine3 fluorescent dye for сlick сhemistry.
  • Cyanine3.5 azide
    Cyanine3.5 azide for biomolecule labeling through click chemistry.
  • Cyanine3B azide
    Azide derivative of Cyanine3B fluorescent dye for сlick сhemistry.
  • Cyanine5 azide
    Cyanine5 azide is a reagent for click chemistry labeling with Cyanine5, a popular fluorescent dye.
  • Cyanine5.5 azide
    Far red / near infrared fluorescent Cyanine5.5 dye derivative for click chemistry.
  • Cyanine7 azide
    Near-infrared (NIR) fluorescent dye for click chemistry labeling.
  • Cyanine7.5 azide
    Long-wavelength NIR fluorescent dye azide for click chemistry.
  • DusQ 3 azide
    DusQ 3 dark quencher with azido group for the conjugation with alkyne-containing molecules
  • FAM azide, 5-isomer
    FAM (fluorescein) azide for сlick chemistry labeling, pure 5-isomer.
  • FAM azide, 6-isomer
    FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for сlick сhemistry.
  • HEX azide, 6-isomer
    Azide of green-yellow emitting HEX dye for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.
  • JOE azide, 5-isomer
    JOE is a chlorinated fluorescein dye which is often used for HEX channel for oligonucleotides. It is less hydrophobic than HEX. This is an azide derivative for сlick chemistry
  • Pyrene azide 1
    Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via click chemistry.
  • Pyrene azide 2
    Pyrene azide with longer triethyleneglycol (PEG3) linker for click chemistry.
  • R110 azide, 6-isomer
    Rhodamine 110 (R110) azide for click chemistry, pure 6-isomer.
  • R6G azide, 5-isomer
    Rhodamine 6G is a xanthene dye that has been used for DNA sequencing and qPCR. This azide derivative is used for the attachment of the dye to DNA and other molecules by means of click chemistry.
  • ROX azide, 5-isomer
    Azide derivative of ROX (Rhodamine X, Rhodamine 101) dye for biomolecule labeling via click chemistry. Pure 5-isomer.
  • ROX azide, 6-isomer
    Azide derivative of ROX (Rhodamine X, Rhodamine 101) dye for biomolecule labeling via click chemistry. Pure 6-isomer.
  • SIMA azide, 6-isomer
    Azide of green-yellow emitting dye SIMA for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.
  • TAMRA azide, 5-isomer
    Azide derivative of TAMRA fluorescent dye for сlick chemistry.
  • TAMRA azide, 6-isomer
    Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free click chemistry reactions with alkynes.
  • TET azide, 6-isomer
    TET is a green-fluorescent fluorescein derivate with spectral properties similar to R6G, JOE, and VIC, widely used for labeling PCR probes. This reagent is an azide for dye conjugation by click chemistry.
  • TR azide, 5-isomer
    Azide derivative of red fluorescent dye TR for сlick сhemistry conjugation. Pure 5-isomer.
  • VIC azide, 6-isomer
    VIC is an asymmetric xanthene dye with spectral properties similar to HEX and JOE, widely used for labeling PCR probes. This derivative is an azide for dye conjugation by click chemistry.
  • sulfo-Cyanine3 azide
    Water-soluble sulfo-Cyanine3 dye azide for click chemistry labeling of sensitive molecules and intact biological objects.
  • sulfo-Cyanine3.5 azide
    Azide derivative of water-soluble sulfo-Cyanine3.5 dye for bioconjugation via click chemistry.
  • sulfo-Cyanine5 azide
    Water soluble sulfo-Cyanine5 fluorescent dye azide for click chemistry.
  • sulfo-Cyanine5.5 azide
    sulfo-Cyanine5.5 azide is a derivative of water-soluble far-red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper-free click chemistry with alkynes and cycloalkynes.
  • sulfo-Cyanine7 azide
    Water-soluble NIR fluorescent dye azide for click chemistry.
  • sulfo-Cyanine7.5 azide
    sulfo-Cyanine7.5 is a very hydrophilic and water-soluble dye for the near-infrared region. The absorption and emission spectra of the dye are similar to Indocyanine Green (ICG), but sulfo-Cyanine7.5 has a much higher fluorescence quantum yield. The dye is a great choice for near-infrared in vivo imaging. This is an azide for click chemistry.

Alkynes

Fluorescent dye alkynes for copper-catalyzed сlick сhemistry. Contain terminal alkyne group.
Group tags Near infrared (NIR) imaging, AF 488, AF 568, BDP® R6G, sulfo-Cyanine3.5, sulfo-Cyanine5.5, NHS esters, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, BDP® 558/568, Cyanine5, BDP® 650/665, FAM (Fluorescein), BDP® FL, BDP® TMR, Cyanine7.5, Perylene, BDP® 581/591, ROX (Rhodamine X, Rhodamine 101), Cyanine3, AF 430, Pyrene, JOE, TAMRA (TMR, Tetramethylrhodamine), Alkynes, R6G, Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, BDP® 630/650, BDP® TR, Click chemistry, Super-resolution imaging, sulfo-Cyanine5
  • 1-Ethynyl pyrene
    Pyrene is a polyaromatic hydrocarbon containing four fused rings. This reagent contains a terminal alkyne group for click chemistry and other reactions, such as Sonogashira coupling.
  • 3-Ethynylperylene
    Alkyne derivative of ultra-bright and photostable perylene fluorophore.
  • AF 430 alkyne
    Alkyne derivative of yellow-green fluorescent dye AF 430 for copper-catalyzed click reaction with azides.
  • AF 488 alkyne
    Alkyne derivative of AF 488 dye for copper-catalyzed cycloaddition to azides. Pure 5-isomer.
  • AF 568 alkyne
    AF 568 derivative designed for fluorescence microscopy and flow cytometry. Pure 5-isomer.
  • BDP® 558/568 alkyne
    BDP 558/568 is a borondipyrromethene dye for Cyanine3-channel. This product is a terminal alkyne derivative for copper-catalyzed click chemistry.
  • BDP® 581/591 alkyne
    BDP 581/591 is a borondipyrromethene fluorophore useful for fluorescence polarization assays, microscopy, and two-photon experiments. This alkyne is a derivative for copper-catalyzed click chemistry.
  • BDP® 630/650 alkyne
    Alkyne dye for copper-catalyzed click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for the red channel.
  • BDP® 650/665 alkyne
    BDP 650/665 is a bright borondipyrromethene red-emitting dye. The terminal ethynyl group of BDP 650/665 alkyne can be easily conjugated with various azides using a copper-catalyzed click reaction.
  • BDP® FL alkyne
    Borondipyrromethene dye alkyne for click chemistry. Bright and photostable dye for FAM channel.
  • BDP® R6G alkyne
    Terminal alkyne derivative of BDP R6G dye for сlick chemistry. BDP R6G is a borondipyrromethene dye whose absorption and emission spectra are similar to R6G (rhodamine 6G).
  • BDP® TMR alkyne
    Borondipyrromethene dye for TAMRA channel, with alkyne group for copper-catalyzed click chemistry.
  • BDP® TR alkyne
    BDP TR is a fluorophore for ROX channel. This borondipyrromethene dye is very bright, and resistant to oxidation.
  • Cyanine3 alkyne
    Cyanine3 alkyne is a fluorescent dye alkyne for сlick сhemistry.
  • Cyanine5 alkyne
    Cyanine5 alkyne is an alkyne dye for click chemistry labeling of biomolecules.
  • Cyanine5.5 alkyne
    Cyanine5.5 alkyne is a NIR (near infrared) dye azide for copper-catalyzed сlick сhemistry.
  • Cyanine7 alkyne
    Cyanine7 alkyne is a near infrared (NIR) dye alkyne for click chemistry.
  • Cyanine7.5 alkyne
    Reactive near infrared (NIR) dye for click chemistry containing a terminal alkyne group.
  • FAM alkyne, 5-isomer
    FAM alkyne, 5-isomer - an alkyne derivative of fluorescein dye for click chemistry.
  • FAM alkyne, 6-isomer
    Fluorescein dye alkyne for click chemistry conjugation, pure 6-isomer.
  • JOE alkyne, 6-isomer
    JOE dye alkyne derivative for copper-catalyzed click chemistry reaction with azides. JOE dye is widely used for nucleic acid labeling.
  • R6G alkyne, 6-isomer
    R6G (rhodamine 6G) terminal alkyne for copper-catalyzed click chemistry reaction with azides. Pure 6-isomer of the dye.
  • ROX alkyne, 5-isomer
    An alkyne derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-catalyzed click chemistry bioconjugation. Pure 5-isomer.
  • ROX alkyne, 6-isomer
    An alkyne derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-catalyzed click chemistry bioconjugation. Pure 6-isomer.
  • TAMRA alkyne, 5-isomer
    Alkyne derivative of TAMRA dye, pure 5-isomer for сopper-catalyzed сlick chemistry.
  • TAMRA alkyne, 6-isomer
    Terminal alkyne for copper-catalyzed click chemistry. Tetramethylrhodamine (TAMRA) is a rhodamine dye which is popular in qPCR and other applications. TAMRA is a also a FRET acceptor for FAM.
  • sulfo-Cyanine3 alkyne
    A water-soluble dye alkyne for copper-catalyzed click chemistry. The fluorophore sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.
  • sulfo-Cyanine3.5 alkyne
    Alkyne derivative of water-soluble sulfo-Cyanine3.5 dye for copper-catalyzed click chemistry.
  • sulfo-Cyanine5 alkyne
    sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for click chemistry.
  • sulfo-Cyanine5 alkyne NHS ester
    Bifunctional derivative of sulfo-Cyanine5 dye containing reactive groups of terminal alkyne and NHS ester.
  • sulfo-Cyanine5.5 alkyne
    Alkyne functionalized, water soluble far red/near infrared emitting fluorophore sulfo-Cyanine5.5.
  • sulfo-Cyanine7 alkyne
    A sulfonated near-infrared dye alkyne for copper-catalyzed cycloaddition with azides.
  • sulfo-Cyanine7.5 alkyne
    sulfo-Cyanine7.5 is a near-infrared fluorophore similar to Indocyanine Green (ICG) but possesses higher fluorescence quantum yield. This is an alkyne for copper-catalyzed click chemistry.

Maleimides

Dye maleimides are thiol-reactive fluorescent dyes for the labeling of sulfhydryl (thiol) groups in proteins.
Group tags Near infrared (NIR) imaging, AF 488, Cyanine3B, BDP® R6G, sulfo-Cyanine5.5, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, BDP® 558/568, Cyanine5, BDP® 650/665, FAM (Fluorescein), BDP® FL, BDP® TMR, Maleimides, Cyanine7.5, BDP® 581/591, ROX (Rhodamine X, Rhodamine 101), Cyanine3, AF 430, Pyrene, TAMRA (TMR, Tetramethylrhodamine), Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, AF 647, BDP® 630/650, BDP® TR, sulfo-Cyanine5
  • AF 430 maleimide
    AF 430 is a green-yellow emitting fluorescent dye of the coumarin series. This maleimide derivative allows the labeling of thiolated biomolecules.
  • AF 488 maleimide
    AF 488 C6 maleimide is a thiol-reactive dye for labeling of protein SH groups.
  • AF 647 maleimide
    AF 647 maleimide is a thiol-reactive far-red fluorescent dye for labeling of thiolated biomolecules (proteins, oligonucleotides, etc.).
  • BDP® 558/568 maleimide
    Maleimide derivative of boron-dipyrromethene dye BDP 558/568, which emits fluorescence in the yellow range; BDP 558/568 maleimide can be used for modification of thiol groups in biomolecules.
  • BDP® 581/591 maleimide
    Thiol reactive maleimide derivative of BDP 581/591 dye. The fluorophore is useful for a variety of application, including fluorescence polarization assays, and microscopy.
  • BDP® 630/650 maleimide
    BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.
  • BDP® 650/665 maleimide
    This maleimide is a thiol-reactive derivative of BDP 650/665, a borondipyrromethene dye for the Cyanine5 (Cy5) channel.
  • BDP® FL maleimide
    BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy.
  • BDP® R6G maleimide
    BDP R6G is a borondipyrromethene dye tuned to R6G (rhodamine 6G) channel. This is a thiol reactive maleimide for the labeling of protein cysteine residues, and other thiols.
  • BDP® TMR maleimide
    A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.
  • BDP® TR maleimide
    BDP TR is a multi-purpose fluorophore with absorption and emission channels matching ROX dye. BDP TR is suitable for two photon, and fluorescence polarization studies.
  • Cyanine3 maleimide
    Cyanine3 maleimide is a thiol mono-reactive dye for protein labeling.
  • Cyanine3B maleimide
    Derivative of a Cyanine3B dye, improved Cyanine3 dye to have higher quantum yield, for maleimide reaction chemistry.
  • Cyanine5 maleimide
    Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.
  • Cyanine5.5 maleimide
    Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.
  • Cyanine7 maleimide
    Cyanine7 maleimide is a sulfhydryl-reactive NIR dye for labeling of proteins.
  • Cyanine7.5 maleimide
    Cyanine7.5 maleimide is a thiol reactive near-infrared dye for labeling of protein SH groups.
  • FAM maleimide, 6-isomer
    Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.
  • Pyrene maleimide
    Pyrene maleimide derivative for the labeling of thiol groups. Pyrene is a useful excimer-forming proximity probe.
  • ROX maleimide, 5-isomer
    ROX maleimide is a thiol reactive dye derivative based on isomerically bright rhodamine X fluorophore.
  • TAMRA maleimide, 5-isomer
    Maleimide derivative of TAMRA (tetramethylrhodamine) for the labeling of thiol groups. Pure 5-isomer of TAMRA.
  • TAMRA maleimide, 6-isomer
    TAMRA is a well-known xanthene dye of the rhodamine series. This reagent is a thiol-reactive maleimide for the labeling of SH groups in proteins and peptides. Pure 6-isomer.
  • sulfo-Cyanine3 maleimide
    Water soluble thiol-reactive derivative of sulfo-Cyanine3, a Cy3 analog.
  • sulfo-Cyanine5 maleimide
    Thiol reactive maleimide, water soluble cyanine dye for Cy5 channel.
  • sulfo-Cyanine5.5 maleimide
    sulfo-Cyanine5.5 is a water-soluble far-red emitting dye. This is a thiol-reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.
  • sulfo-Cyanine7 maleimide
    Water-soluble near-infrared dye maleimide for the labeling of proteins and peptides.
  • sulfo-Cyanine7.5 maleimide
    sulfo-Cyanine7.5 is a highly hydrophilic near infrared dye for in vivo imaging. This maleimide derivative is useful for the labeling of thiol groups of proteins and peptides.

Hydrazides

Dye hydrazides are carbonyl-reactive fluorescent dyes for the labeling of aldehydes and ketones.
Group tags Near infrared (NIR) imaging, AF 488, BDP® R6G, Cyanine7, BDP® 558/568, Cyanine5, FAM (Fluorescein), BDP® FL, Cyanine7.5, BDP® 581/591, Cyanine3, AF 430, Pyrene, TAMRA (TMR, Tetramethylrhodamine), Hydrazides, Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, BDP® 630/650, BDP® TR, sulfo-Cyanine5
  • AF 430 hydrazide
    AF 430 hydrazide is a carbonyl-reactive dye for conjugating with aldehydes and ketones.
  • AF 488 hydrazide
    AF 488 hydrazide is a carbonyl-reactive dye for conjugating with aldehydes and ketones.
  • BDP® 558/568 hydrazide
    BDP 558/568 hydrazide is a carbonyl-reactive dye that emits in the orange/yellow part of the spectrum.
  • BDP® 581/591 hydrazide
    BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.
  • BDP® 630/650 hydrazide
    A carbonyl reactive borondipyrromethene based dye for the red channel (Cyanine5).
  • BDP® FL hydrazide
    Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.
  • BDP® R6G hydrazide
    BDP R6G hydrazide is a borondipyrromethene dye whose absorption and emission spectra resemble R6G. This is a carbonyl-reactive compound.
  • BDP® TR hydrazide
    BDP TR hydrazide for the labeling of carbonyl compounds with BDP TR, a borondipyrromethene matching ROX channel.
  • Cyanine3 hydrazide
    Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.
  • Cyanine5 hydrazide
    Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.
  • Cyanine5.5 hydrazide
    Cyanine5.5 hydrazide is a carbonyl reactive NIR dye which is particularly suitable for the labeling of periodate oxidized glycoproteins, i.e. antibodies.
  • Cyanine7 hydrazide
    Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.
  • Cyanine7.5 hydrazide
    Near infrared fluorophore functionalized with hydrazide moiety. Reactive against carbonyl compounds, useful for the labeling of saccharides, and antibodies after periodate oxidation.
  • FAM hydrazide, 5-isomer
    FAM hydrazide is a carbonyl reactive fluorescein derivative. Pure 5-isomer. Can label oxidized proteins, saccharides, and many small molecules with carbonyl groups.
  • FAM hydrazide, 6-isomer
    6-FAM hydrazide is a carbonyl reactive fluorescein (FAM) derivative. This product contains a pure 6-isomer of fluorescein.
  • Pyrene hydrazide
    Pyrene hydrazide is a carbonyl-reactive dye for conjugating with aldehydes and ketones.
  • TAMRA hydrazide, 6-isomer
    6-TAMRA azide is a carbonyl reactive hydrazide derivative of tetramethylrhodamine (TAMRA) fluorophore.
  • sulfo-Cyanine3 hydrazide
    Cyanine3 hydrazide with sulfo groups, well soluble in water and readily reacting with carbonyl compounds.
  • sulfo-Cyanine5 hydrazide
    Cyanine5 hydrazide containing sulfo groups, with good water solubility and carbonyl compounds reactivity.

Carboxylic acids

Carboxylic acid derivatives of fluorescent dyes. Can be used for the labeling of amines after pre-activation with carbodiimides, and also for Steglich esterification of alcohols.
Group tags Near infrared (NIR) imaging, DusQ 21, AF 488, Crosslinking, Cyanine3B, AF 568, Calibro® Fluor 610, BDP® R6G, sulfo-Cyanine3.5, sulfo-Cyanine5.5, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, BDP® 558/568, Cyanine5, TET (Tetrachlorofluorescein), AF 594, AF 555, BDP® 576/589, BDP® FL, AF 532, BDP® TMR, Carboxylic acids, Cyanine3.5, Cyanine7.5, BDP® 581/591, ROX (Rhodamine X, Rhodamine 101), Cyanine3, AF 430, Pyrene, TAMRA (TMR, Tetramethylrhodamine), ATT 594, Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, BDP® 564/570, AF 647, VIC, BDP® 630/650, BDP® TR, ATT 550, SIMA (Dichloro-diphenyl-fluorescein), HEX (Hexachlorofluorescein), TR, sulfo-Cyanine5, AF 343 (Coumarin), AMCA
  • AF 343 (Coumarin)-X-carboxylic acid
    AF 343 (Coumarin) carboxylic acid. Extended aminohexanoyl linker increases solubility and provides spatial separation between the fluorophore, and the functional group.
  • AF 430 carboxylic acid
    Non-reactive form of AF 430 fluorescent dye to be used as a reference standard.
  • AF 488 carboxylic acid
    AF 488 carboxyl derivative can be used as a reference standard or for synthesizing various AF488 esters.
  • AF 532 carboxylic acid
    Non-reactive form of AF 532 fluorescent dye with a free carboxyl group.
  • AF 555 carboxylic acid
    Non-reactive form of AF 555 fluorescent dye with a free carboxyl group.
  • AF 568 carboxylic acid
    Non-reactive form of AF 568 fluorescent dye with a free carboxyl group.
  • AF 594 carboxylic acid
    Non-reactive form of AF 594 fluorescent dye with a free carboxyl group.
  • AF 647 carboxylic acid
    AF 647 carboxylic acid is a water-soluble dye that can be used as a reference standard for dye conjugates and the synthesis of AF647-containing biomolecules.
  • AMCA carboxylic acid
    Non-reactive form of AMCA fluorescent dye with a free carboxyl group. AMCA is one of the brightest blue fluorescent dyes with large Stoke's shift and high resistance to photobleaching.
  • ATT 550 carboxylic acid
    Derivative of АТТ 550 fluorophore with non-activated free carboxylic acid group.
  • ATT 594 carboxylic acid
    Derivative of water-soluble red-fluorescent dye АТТ 594 with non-activated free carboxylic acid group.
  • BDP® 558/568 carboxylic acid
    BDP 558/568 is a borondipyrromethene dye with yellow emission. The dye as a carboxylic acid can be used in peptide synthesis (after appropriate activation of the carboxylic group).
  • BDP® 564/570 carboxylic acid
    A derivative of BDP 564/570 fluorophore with a free carboxylic acid functional group. The dye has an emission in the orange part of the spectrum.
  • BDP® 576/589 carboxylic acid
    Derivative of BDP 576/589 fluorophore with non-activated free carboxylic acid group.
  • BDP® 581/591 carboxylic acid
    BDP 581/591 is a multi purpose fluorophore, that can also be used to probe reactive oxygen species (ROS). This is a carboxylic acid derivative with a free COOH group.
  • BDP® 630/650 carboxylic acid
    BDP 630/650 is a bright fluorophore for far red part of the spectrum. This dye is perfect for microscopy and fluorescence polarization assays. This is a carboxylic acid that can be activated for the coupling, or used as a control.
  • BDP® FL carboxylic acid
    Borondipyrromethene dye for fluorescein (FAM) channel, free unactivated carboxylic acid useful as a negative control, and for the calibration.
  • BDP® R6G carboxylic acid
    Free carboxylic acid derivative of BDP R6G - a borondipyrromethene dye with absorption and emission spectra resembling R6G rhodamine.
  • BDP® TMR carboxylic acid
    Borondipyrromethene dye for TMR channel with a non-activated carboxylic acid group.
  • BDP® TR carboxylic acid
    BDP TR is a borondipyrromethene dye for ROX channel. This is a carboxy derivative bearing free COOH group for the conjugation with alcohols by Steglich esterification, or for the use in non-conjugated form.
  • Calibro® Fluor 610 carboxylic acid
    Carboxyl derivative of Calibro® Fluor 610, a red-emitting fluorescent dye specifically designed for qPCR applications. It can be used as a reference standard or for synthesizing various Calibro® Fluor 610 esters.
  • Cyanine3 carboxylic acid
    The free carboxylic acid of Cyanine3 dye. Non-sulfonated dye, with good solubility in organic solvents, and limited aqueous solubility.
  • Cyanine3.5 carboxylic acid
    Unactivated monofunctional Cy3.5 carboxylic acid. Can be used as a reference non-reactive dye or control.
  • Cyanine3B carboxylic acid
    A Cyanine3B derivative with unactivated free carboxy group for use as a control, calibration, and conjugation after pre-activation.
  • Cyanine5 carboxylic acid
    Cyanine5 carboxylic acid, unactivated dye. An analog of Cy5®; free carboxylic acid.
  • Cyanine5.5 carboxylic acid
    Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications.
  • Cyanine7 carboxylic acid
    The unactivated free carboxylic acid of near-infrared fluorescent dye Cyanine7.
  • Cyanine7 dicarboxylic acid
    Cyanine7 dicarboxylic acid is a bifunctional dye molecule possessing two carboxylic acid groups.
  • Cyanine7.5 carboxylic acid
    Cyanine7.5 carboxylic acid - unactivated NIR cyanine dye carboxylic acid.
  • DusQ 21 carboxylic acid
    DusQ 21 is a non-fluorescent quencher molecule for far red and NIR range
  • HEX carboxylic acid, 6-isomer
    Derivative of HEX fluorophore with non-activated free carboxylic acid group.
  • Pyrenebutyric acid
    A derivative of pyrene containing a free carboxylic acid function. Pyrene is a polycyclic aromatic hydrocarbon (PAH) which exhibits excimer fluorescence and affinity to graphite.
  • ROX carboxylic acid, 6-isomer
    Derivative of ROX (Rhodamine X, Rhodamine 101) fluorophore with non-activated free carboxylic acid group. This reagent is a pure 6-isomer.
  • SIMA carboxylic acid, 6-isomer
    Derivative of SIMA fluorophore with non-activated free carboxylic acid group.
  • TAMRA carboxylic acid, 5-isomer
    Non-reactive form of TAMRA fluorescent dye with a free carboxyl group. Pure 5-isomer.
  • TET carboxylic acid, 6-isomer
    Derivative of TET fluorophore with non-activated free carboxylic acid group.
  • TR-X-carboxylic acid, 5-isomer
    Carboxyl derivative of TR, a red-emitting fluorescent dye. It can be used as a reference standard or for synthesizing various TR esters. The extended aminohexanoyl linker increases solubility and provides spatial separation between the fluorophore and the functional group.
  • VIC carboxylic acid, 6-isomer
    Derivative of VIC fluorophore with non-activated free carboxylic acid group. VIC is an asymmetric xanthene dye with spectral properties similar to HEX and JOE, widely used for labeling PCR probes.
  • sulfo-Cyanine3 carboxylic acid
    sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.
  • sulfo-Cyanine3.5 carboxylic acid
    Derivative of water-soluble sulfo-Cyanine3.5 dye containing a non-activated free carboxylic acid group.
  • sulfo-Cyanine5 carboxylic acid
    Water-soluble Cyanine5 carboxylic acid, non-activated fluorescent dye.
  • sulfo-Cyanine5.5 carboxylic acid
    Water-soluble far-red fluorescent dye sulfo-Cyanine5.5 in the form of free non-activated carboxylic acid. The dye is useful for calibration and as a non-reactive control.
  • sulfo-Cyanine7 carboxylic acid
    sulfo-Cyanine7 carboxylic acid is a non-reactive fluorescent dye that can be used as a NIR (near-infrared) marker.
  • sulfo-Cyanine7 dicarboxylic acid
    sulfo-Cyanine7 dicarboxylic acid is a bifunctional dye with two carboxyl groups.
  • sulfo-Cyanine7.5 carboxylic acid
    Water-soluble, near-infrared fluorescent dye in the form of carboxylic acid. The dye has high hydrophilicity due to the presence of four sulfo groups.
  • sulfo-Cyanine7.5 dicarboxylic acid
    sulfo-Cyanine7.5 dicarboxylic acid is a bifunctional cyanine dye with two carboxylic acid (COOH) groups. The molecule can be used to construct cross conjugates containing a near-infrared emitting fluorophore.

Amines

Fluorescent dyes with free amino groups, for the coupling with various electrophilic compounds like activated esters and epoxides.
Group tags Near infrared (NIR) imaging, AF 488, Cyanine3B, BDP® R6G, sulfo-Cyanine3.5, sulfo-Cyanine5.5, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, BDP® 558/568, Cyanine5, FAM (Fluorescein), BDP® FL, BDP® TMR, Cyanine7.5, BDP® 581/591, ROX (Rhodamine X, Rhodamine 101), Cyanine3, AF 430, TAMRA (TMR, Tetramethylrhodamine), Fluorescence polarization, Cyanine5.5, sulfo-Cyanine3, BDP® 630/650, BDP® TR, sulfo-Cyanine5, Amines
  • AF 430 amine
    AF 430 dye with a terminal amino group with emission in the yellow-green region of the spectrum.
  • AF 488 amine
    AF 488 dye with a terminal amino group with emission in the green region of the spectrum.
  • BDP® 558/568 amine
    BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. This amine derivative can be conjugated using reactions with various electrophiles.
  • BDP® 581/591 amine
    BDP 581/591 fluorophore derivative with free amine group for the conjugation with electrophilic reagents, and enzymatic transamination.
  • BDP® 630/650 amine
    BDP 630/650 is a far red emitting fluorophore for Cyanine5 channel. This fluorophore is based on BDP (borondipyrromethene) core, which provides high quantum yield and photostability. This is an amine derivative of this dye.
  • BDP® FL amine
    Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.
  • BDP® R6G amine
    Amine derivative of BDP R6G, borondipyrromethene dye matching Rhodamine 6G (R6G) channel. The terminal aliphatic amine group can be conjugated with various electrophiles.
  • BDP® TMR amine
    BDP TMR amine is an amino dye for TAMRA channel. The dye possesses bright fluorescence and is well suitable for the fluorescence polarization assays.
  • BDP® TR amine
    BDP TR borondipyrromethene dye with a free amine group for the conjugation with electrophilic reagents and enzymatic transamination reaction. BDP TR is a bright dye for the ROX channel.
  • Cyanine3 amine
    Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.
  • Cyanine3B amine
    Amino derivative of Cyanine3B, a reactive dye with significantly increased fluorescence quantum yield and photostability for the conjugation with activated esters and epoxides.
  • Cyanine5 amine
    Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
  • Cyanine5.5 amine
    Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.
  • Cyanine7 amine
    Cy7 amine is a near-infrared dye with free amine group for the conjugation with activated esters and other reactive molecules.
  • Cyanine7.5 amine
    Near-infrared dye Cyanine7.5 with free amino group which can be coupled with activated carboxylic acid derivatives.
  • FAM amine, 5-isomer
    Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.
  • FAM amine, 6-isomer
    Amine derivative of fluorescein (FAM) fluorophore, pure 6-isomer, for the enzymatic transamination labeling, reactions with electrophilic reagents, and reductive amination.
  • ROX amine, 6-isomer
    An amine derivative of ROX (Rhodamine X, Rhodamine 101) dye that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling. Pure 6-isomer.
  • TAMRA amine, 5-isomer
    TAMRA (tetramethylrhodamine) dye, pure 5-isomer, with an amine group for the conjugation with electrophilic reagents (NHS esters, epoxides, etc).
  • sulfo-Cyanine3 amine
    Water soluble cyanine dye with bright fluorescence and high extinction coefficient. Contains an amino group for the conjugation with electrophiles and enzymatic transamination labeling.
  • sulfo-Cyanine3.5 amine
    Sulfonated Cyanine3.5 amine derivative for the conjugation with electrophiles and enzymatic transamination labeling.
  • sulfo-Cyanine5 amine
    Sulfonated Cyanine5 amine derivative for the conjugation with electrophiles and enzymatic transamination labeling.
  • sulfo-Cyanine5.5 amine
    sulfo-Cyanine5.5 is a far-red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. This is an amine derivative that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling.
  • sulfo-Cyanine7 amine
    NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.
  • sulfo-Cyanine7.5 amine
    Near-infrared, water-soluble, hydrophilic dye with amine functional group.

Tetrazines

Tetrazines are derivatives that react with terminal alkenes, trans-cyclooctenes, cyclopropenes, and other activated olefins via an inverted electron demand [4+2]-cycloaddition - an example of copper-free click chemistry reaction.
Group tags Near infrared (NIR) imaging, Cyanine3B, BDP® R6G, sulfo-Cyanine5.5, Cyanine7, sulfo-Cyanine7, Copper-free click chemistry, BDP® 558/568, Tetrazines, Cyanine5, AF 594, FAM (Fluorescein), BDP® 576/589, BDP® FL, BDP® TMR, Cyanine7.5, BDP® 581/591, ROX (Rhodamine X, Rhodamine 101), Cyanine3, AF 430, Cyanine5.5, sulfo-Cyanine3, BDP® 630/650, BDP® TR, Super-resolution imaging, sulfo-Cyanine5
  • AF 430 tetrazine
    Tetrazine derivative of AF 430 fluorescent dye suitable for in vitro cell labeling.
  • AF 594 tetrazine, 6-isomer
    Tetrazine derivative of AF 594 fluorophore for TCO ligation and in vitro labeling.
  • BDP® 558/568 tetrazine
    Stable fluorophore that can be conjugated with trans-cyclooctene derivatives of biomolecules for their visualization.
  • BDP® 576/589 tetrazine
    Tetrazine derivative of BDP 576/589 hydrophobic dye for conjugation with trans-cyclooctenes and cyclopropenes in the TCO ligation reaction.
  • BDP® 581/591 tetrazine
    BDP 581/591 is a borondipyrromethene dye with a tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.
  • BDP® 630/650 tetrazine
    BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.
  • BDP® FL tetrazine
    BDP FL tetrazine (methyltetrazine) is a reactive dye for the inverse electron demand Diels-Alder (IEDDA) reaction with trans-cyclooctenes, cyclopropenes, and other strained cycloolefines. BDP FL is a bright and photostable dye for the 488 nm fluorescein (FAM) channel.
  • BDP® R6G tetrazine
    BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to those of rhodamine 6G. It contains a tetrazine fragment for IEDDA ligation.
  • BDP® TMR tetrazine
    A fluorophore for the TAMRA channel with a functional group that can form conjugates in click chemistry reactions (IEDDA ligation) .
  • BDP® TR tetrazine
    BDP TR is a borondipyrromethene fluorophore for the ROX channel. The dye produces bright fluorescent emission. Tetrazines are reactive components for the conjugation with strained cycloalkenes.
  • Cyanine3 tetrazine
    Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.
  • Cyanine3B tetrazine
    Cyanine3B dye tetrazine derivative for IEDDA conjugation with strained olefins and terminal alkenes.
  • Cyanine5 tetrazine
    Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.
  • Cyanine5.5 tetrazine
    A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.
  • Cyanine7 tetrazine
    Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.
  • Cyanine7.5 tetrazine
    Cyanine7.5 tetrazine is a tetrazine derivative for TCO ligation and Diels-Alder reaction containing a NIR fluorophore and suitable for in vivo infrared imaging.
  • FAM tetrazine, 5-isomer
    FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.
  • FAM tetrazine, 6-isomer
    This molecule is a conjugate of bright fluorophore FAM (fluorescein) and tetrazine, a reactive group that reacts with trans-cycloalkenes in a reaction called IEDDA (inverse electron demand Diels-Alder reaction).
  • ROX tetrazine, 5-isomer
    A tetrazine derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-free bioconjugation. Pure 5-isomer.
  • sulfo-Cyanine3 tetrazine
    Water-soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.
  • sulfo-Cyanine5 tetrazine
    Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.
  • sulfo-Cyanine5.5 tetrazine
    Tetrazine derivative of water-soluble far-red emitting fluorescent dye sulfo-Cyanine5.5 for TCO ligation with trans-cyclooctenes and other strained olefins.
  • sulfo-Cyanine7 tetrazine
    Near infrared, water soluble dye methyltetrazine for the conjugation with strained cycloalkenes in TCO ligation reaction.

Cycloalkynes

Dyes possessing cycloalkyne moieties for copper-free сlick chemistry.
Group tags Near infrared (NIR) imaging, AF 488, Cyanine3B, AF 568, BDP® R6G, sulfo-Cyanine5.5, Cyanine7, sulfo-Cyanine7, Copper-free click chemistry, BDP® 558/568, Cyanine5, BDP® 650/665, Cycloalkynes, FAM (Fluorescein), AF 555, BDP® FL, BDP® TMR, Cyanine3.5, BDP® 581/591, ROX (Rhodamine X, Rhodamine 101), Cyanine3, TAMRA (TMR, Tetramethylrhodamine), Cyanine5.5, sulfo-Cyanine3, AF 647, BDP® TR, Super-resolution imaging, sulfo-Cyanine5
  • AF 488 DBCO
    Dibenzocyclooctyne (DBCO, ADIBO) containing the green fluorophore AF 488 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples. Pure 5-isomer.
  • AF 555 DBCO
    Dibenzocyclooctyne (DBCO, ADIBO) containing the yellow fluorophore AF 555 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
  • AF 568 DBCO
    Dibenzocyclooctyne (DBCO, ADIBO) containing the orange fluorophore AF 568 for cooper-free labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
  • AF 647 DBCO
    Dibenzocyclooctyne (DBCO, ADIBO) derivative of the far red fluorophore AF 647 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
  • BDP® 558/568 DBCO
    BDP 558/568 DBCO is a bright and photostable dye with emission in the yellow spectrum range. It contains a cyclooctyne substituting group (i.e. DBCO), which can react with various azides in Click Chemistry reactions.
  • BDP® 581/591 DBCO
    BDP 581/591 is a borondipyrromethene dye that can be used not only as a fluorescent dye, but also as a ROS probe. It can be conjugated with azides using copper-free click chemistry.
  • BDP® 650/665 DBCO
    This red-fluorescent dye contains a substituting group for copper-free click chemistry.
  • BDP® FL DBCO
    BDP FL DBCO is a dye cyclooctyne for copper-free click chemistry reactions with azides. Its absorption and emission wavelengths correspond to those of fluorescein (FAM), but BDP FL is significantly more photostable.
  • BDP® R6G DBCO
    A derivative of BDP R6G dye with azodibenzocyclooctyne (DBCO or ADIBO) for copper-free click chemistry conjugation with azides.
  • BDP® TMR DBCO
    This yellow-orange-fluorescent boron dipyrromethene dye contains a DBCO substituting group for participation in click chemistry reactions.
  • BDP® TR DBCO
    A dye with a dibenzocyclooctyne substituting group for the ROX channel.
  • Cyanine3 DBCO
    Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper-free click chemistry.
  • Cyanine3.5 DBCO
    Cyclooctyne derivative of Cyanine3.5 dye, which easily reacts with various azides resulting in stable conjugates.
  • Cyanine3B DBCO
    Dibenzocyclooctyne (DBCO, ADIBO) containing Cyanine3B fluorophore for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples.
  • Cyanine5 DBCO
    Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper-free click chemistry.
  • Cyanine5.5 DBCO
    Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for copper-free click chemistry.
  • Cyanine7 DBCO
    NIR fluorescent dye functionalized with cyclooctyne moiety for copper free click chemistry conjugation with azides.
  • FAM DBCO, 6-isomer
    Cyclooctyne derivative of fluorescein (FAM) for copper-free click chemistry reaction with azides. Pure 6-isomer of fluorescein.
  • ROX DBCO, 5-isomer
    ROX (rhodamine X) is a bright rhodamine dye. This is a DBCO (dibenzocyclooctyne) derivative that has high reactivity against azides.
  • TAMRA DBCO, 5-isomer
    Cyclooctyne derivative of tetramethylrhodamine (TMR, TAMRA) for copper-free click chemistry conjugation with azides. Pure 5-isomer.
  • sulfo-Cyanine3 DBCO
    sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water-soluble fluorophore sulfo-Cyanine3 for copper-free click chemistry.
  • sulfo-Cyanine5 DBCO
    Water-soluble cycloalkyne for copper-free click chemistry reaction with azides. A derivative of sulfo-Cyanine5.
  • sulfo-Cyanine5.5 DBCO
    Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free click reaction with azides.
  • sulfo-Cyanine7 DBCO
    Dibenzocyclooctyne (DBCO, or ADIBO) conjugated with sulfo-Cyanine7, a water-soluble near-IR dye for labeling azide-containing biomolecules inside living cells, whole organisms, and inanimate samples.

Miscellaneous dyes

Non-functionalized fluorophores for technical applications.
Group tags Near infrared (NIR) imaging, sulfo-Cyanine7.5, Cyanine5, BDP® FL, ICG (Indocyanine Green), Cyanine3.5, Cyanine7.5, Cyanine3, Nuclei, Flow cytometry, Dimethyls, Cyanine5.5, sulfo-Cyanine3, Microscopy, sulfo-Cyanine5, Protein labeling
  • 3,5-Dimethyl-BDP®
    Boron dipyrromethene (BDP)-based derivative with fluorescence in gas phase.
  • BDP® FL L-Cystine
    BDP FL L-cystine is a symmetric disulfide for reversible thiol-specific labeling of thiolated oligonucleotides, proteins, and cells.
  • Cyanine3 dimethyl
    Non-functionalized Сyanine3 dye derivative with an aliphatic side chain.
  • Cyanine3.5 dimethyl
    Non-functionalized Сyanine3.5 dye derivative with good solubility in organic solvents and bright fluorescence in the yellow-orange spectrum range.
  • Cyanine5 dimethyl
    Non-functionalized Сyanine5 dye derivative with good solubility in organic solvents and bright fluorescence in the red spectrum range.
  • Cyanine5.5 dimethyl
    Non-functionalized Сyanine5.5 dye derivative with good solubility in organic solvents and bright fluorescence in the far-red spectrum range.
  • Cyanine7.5 dimethyl
    Non-functionalized Сyanine7.5 dye derivative with an aliphatic side chain.
  • Indocyanine Green (ICG)
    Water-soluble and pH-insensitive fluorescent dye widely used in imaging and flow cytometry.
  • TechnoDye 498/505
    TechnoDye 498/505 is a water soluble technical fluorophore with unity quantum yield.
  • TechnoDye 502/512
    Highly fluorescent and photostable fluorophore with excitation spectrum in the green range.
  • Thiazole Orange
    Cyanine dye that is essentially dark in solution but has a bright fluorescence in double-stranded DNA and RNA complexes.
  • sulfo-Cyanine3 dimethyl
    sulfo-Cyanine3 dimethyl is a non-functionalized, water-soluble cyanine dye with bright yellow fluorescence.
  • sulfo-Cyanine5 dimethyl
    sulfo-Cyanine5 dimethyl is a non-functionalized, water-soluble cyanine dye with bright far-red fluorescence.
  • sulfo-Cyanine7.5 dimethyl
    Non-functionalized NIR fluorescent dye. Water soluble heptamethine cyanine can be used as a tracing material.

Bifunctional dyes

Fluorescent dyes with two functional groups for the labeling of different biomolecules.
Group tags Near infrared (NIR) imaging, Crosslinking, NHS esters, Cyanine7, sulfo-Cyanine7, sulfo-Cyanine7.5, Carboxylic acids, sulfo-Cyanine5

Cycloalkenes

Cycloalkenes are strained alkenes, tetrazine-reactive derivatives for inverse electron-demand Diels-Alder cycloaddition reaction (IEDDA).
Group tags AF 488, Cycloalkenes, Copper-free click chemistry
  • AF 488 TCO
    AF 488-containing derivative of trans-cyclooctene (TCO) for conjugation with tetrazine via the inverse electron-demand Diels-Alder cycloaddition reaction (IEDDA).
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