TAMRA azide, 6-isomer
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A8130 | 1 mg | $110 | in stock | |
| B8130 | 5 mg | $135 | in stock | |
| C8130 | 10 mg | $210 | in stock | |
| D8130 | 25 mg | $390 | in stock | |
| E8130 | 50 mg |
$595
|
in stock | |
| F8130 | 100 mg |
$790
|
in stock |
Tetramethylrhodamine (TAMRA) is a xanthene dye with orange emission. The dye is a FRET acceptor for FAM and is sometimes used as a quencher of FAM.
Like other xanthenes, TAMRA exists as two isomers (5- and 6-) with very similar spectral properties. This is an azide derivative of the 6-isomer of TAMRA. The azide can be conjugated with terminal alkynes using copper-catalyzed click chemistry (CuAAC) or with cycloalkynes with copper-free strain-promoted alkyne azide cycloaddition (SPAAC) reaction.
Absorption and emission spectra of 6-TAMRA
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Phosphate CPG 1000 solid support
Phosphate modifier CPG for the solid phase synthesis of long (up to 120mer) oligonucleotides containing 3 prime phosphate modification.BDP TMR azide
Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.General properties
| Appearance: | violet solid / solution |
| Mass spec M+ increment: | 512.2 |
| Molecular weight: | 512.56 |
| CAS number: | 1192590-89-8 |
| Molecular formula: | C28H28N6O4 |
| Solubility: | Good in DMF, DMSO, alcohols, low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 541 |
| ε, L⋅mol−1⋅cm−1: | 84000 |
| Emission maximum, nm: | 567 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.32 |
| CF280: | 0.19 |
Product citations
- Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
- Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
- Chen, X.; Xu, J.; Wong, N.-K.; Zhong, S.; Yang, M.; Liu, Z.; Lu, Y.; Li, W.; Zhou, Y. Chemoproteomic profiling of cobalamin-independent methionine synthases in plant with a covalent probe. Journal of Agricultural and Food Chemistry, 2020, 68(30), 8050–8056. doi: 10.1021/acs.jafc.0c03301
- Xu, Y.; Deng, Z.; Shi, Y.; Chen, X.; Xu, J.; Zhong, S.; Xiao, Y.; Wong, N.-K.; Zhou, Y. Molecular Imaging and In Situ Quantitative Profiling of Fatty Acid Synthase with a Chemical Probe. Analytical Chemistry, 2020, 92(6), 4419–4426. doi: 10.1021/acs.analchem.9b05327
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