SIMA (Dichloro-diphenyl-fluorescein) in Fluorophores

Absorption max 531 nm Emission max 555 nm Fluorophore chart
SIMA or dichloro-diphenyl-fluorescein is a dye with spectral properties similar to HEX, but with a higher quantum yield. SIMA also has improved stability during deprotection under basic conditions

SIMA azide, 6-isomer

Azide of green-yellow emitting dye SIMA for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.
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Cat. # Quantity Price Lead time
AE230 1 mg $110 in stock
BE230 5 mg $180 in stock
CE230 10 mg $310 in stock
DE230 25 mg $410 in stock
EE230 50 mg $695 in stock
FE230 100 mg $1190 in stock
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SIMA carboxylic acid, 6-isomer

Derivative of SIMA fluorophore with non-activated free carboxylic acid group.
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Cat. # Quantity Price Lead time
2E290 5 mg $125 21 days
4E290 25 mg $225 21 days
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SIMA phosphoramidite, 6-isomer

A phosphoramidite for the synthesis of SIMA-labeled oligonucleotides. SIMA is a more stable analog of HEX.
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Cat. # Quantity Price Lead time
DE260
/ Easily soluble lyophilised form in 8 mL septum
250 mg $202 in stock
EE260
/ Easily soluble lyophilised form in 8 mL septum
500 mg $340 in stock
FE260
/ Easily soluble lyophilised form in 30 mL septum
1 g $575 in stock
HE260 10 g please inquire in stock
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SIMA phosphoramidite, 6-isomer (hydroxyprolinol)

A phosphoramidite (hydroxyprolinol) for the synthesis of SIMA-labeled oligonucleotides. SIMA is a more stable analog of HEX.
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Cat. # Quantity Price Lead time
13360 100 mg $140 in stock
23360 250 mg $340 in stock
43360 1 g $990 in stock
63360 5 g $3900 in stock
83360 10 g please inquire 21 days
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SIMA-dT phosphoramidite, 6-isomer

Phosphoramidite for synthesis of oligonucleotides labeled with SIMA in the middle of sequence.
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Cat. # Quantity Price Lead time
2950-100mg 100 mg $180 in stock
2950-250mg 250 mg $390 in stock
2950-1g 1 g $1120 in stock
2950-5g 5 g $4520 in stock
2950-10g 10 g $8650 in stock
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