Copper(II)-TBTA complex

Cat. # Quantity Price Lead time
21050 1.5 mL
$79.00
in stock
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A component of our recommended catalyst for conjugating azides with alkynes using a copper-catalyzed click reaction. This inactive complex is stable and contains divalent copper(II) as 10 mM CuSO4 in 55% aqueous DMSO.

When Cu(II)-TBTA is treated with reducing agents, such as ascorbic acid, a catalytically active complex with monovalent copper (I) is formed.

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General properties

Appearance: blue solution
Molecular weight: 690.23
Molecular formula: C30H30CuN10O4S
Quality control: functional testing (click chemistry)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Product citations

  1. Varizhuk, I. V.; Stomakhin, A. A.; Ermolaeva, A. N.; Petrova, K. V.; Surzhikov, S. A.; Kolganova, N. A.; Timofeev, E. N. Alpha-2′-Deoxyguanosine Promotes Highly Stable Anti-Parallel G-Quadruplex DNA Structures with Therapeutic Potential via Guided G-Quadruplex Assembly. International Journal of Biological Macromolecules, 2025, 319, 145705. doi: 10.1016/j.ijbiomac.2025.145705
  2. Piranej, S.; Ogasawara, H.; Zhang, L.; Jackson, K.; Bazrafshan, A.; Salaita, K. On-Demand Photoactivation of DNA-Based Motor Motion. ACS Nano, 2025, 19(5), 5363–5375. doi: 10.1021/acsnano.4c13068
  3. Petrovic, D.; Slade, L.; Paikopoulos, Y.; D’Andrea, D.; Savic, N.; Stancic, A.; Miljkovic, J. L.; Vignane, T.; Drekolia, M. K.; Mladenovic, D.; Sutulovic, N.; Refeyton, A.; Kolakovic, M.; Jovanovic, V. M.; Zivanovic, J.; Miler, M.; Vellecco, V.; Brancaleone, V.; Bucci, M.; Casey, A. M.; Yu, C.; Kasarla, S. S.; Smith, K. W.; Kalfe-Yildiz, A.; Stenzel, M.; Miranda-Vizuete, A.; Hergenröder, R.; Phapale, P.; Stanojlovic, O.; Ivanovic-Burmazovic, I.; Vlaski-Lafarge, M.; Bibli, S.-I.; Murphy, M. P.; Otasevic, V.; Filipovic, M. R. Ergothioneine Improves Healthspan of Aged Animals by Enhancing cGPDH Activity through CSE-Dependent Persulfidation. Cell Metabolism, 2025, 37(2), 542-556.e14. doi: 10.1016/j.cmet.2024.12.008
  4. Piranej, S.; Zhang, L.; Bazrafshan, A.; Marin, M.; Melikian, G. B.; Salaita, K. Rolosense: Mechanical Detection of SARS-CoV-2 Using a DNA-Based Motor. ACS Cent. Sci., 2024, 10(7), 1332–1347. doi: 10.1021/acscentsci.4c00312
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