sulfo-Cyanine5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 13320 | 1 mg | $91 | in stock | |
| 23320 | 5 mg | $119 | in stock | |
| 43320 | 25 mg | $345 | in stock | |
| 53320 | 50 mg |
$557
|
in stock | |
| 63320 | 100 mg |
$890
|
in stock |
Water-soluble Cyanine5 succinimidyl ester (SE), an equivalent of Cy5® NHS ester, for the labeling of various amine-containing molecules in aqueous phase without use of any organic co-solvent. This product is, therefore, particularly useful for the labeling of proteins that denature in the presence of organic co-solvents, as well as for proteins with low solubility.
sulfo-Cyanine 5 is an analog of Cy5®, one of the most popular fluorophores, which is compatible with various equipment such as plate readers, microscopes, and imagers.
This dye is highly hydrophilic and water-soluble. A non-sulfonated analog is also available.
Can be used as a replacement for Cy5®, DyLight 649 for all applications.
sulfo-Cyanine5 absorbance and emission spectra
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AF 343 (Coumarin) X azide
AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.Cyanine3 alkyne
Cyanine3 alkyne is a fluorescent dye alkyne for сlick сhemistry.General properties
| Appearance: | dark blue powder |
| Molecular weight: | 777.95 |
| CAS number: | 2230212-27-6; 146368-14-1 (N-Ethyl) |
| Molecular formula: | C36H40N3KO10S2 |
| Solubility: | very good in water, good in DMF and DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 646 |
| ε, L⋅mol−1⋅cm−1: | 271000 |
| Emission maximum, nm: | 662 |
| Fluorescence quantum yield: | 0.28 |
| CF260: | 0.04 |
| CF280: | 0.04 |
Product citations
- Geng, T.; Paek, S.Y.; Leung, E.; Chamley, L.W.; Wu, Z. Comparing extracellular vesicles from four different cell origins for intracellular drug delivery to pancreatic cancer cells: Small or large vesicles?. Journal of drug delivery science and technology, 2024, 93, 105416. doi: 10.1016/j.jddst.2024.105416
- Stinson, B.M.; Carney, S.M.; Walter, J.C.; Loparo, J.J. Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining. Nature Communications, 2024, 15, 1250. doi: 10.1038/s41467-024-45553-z
- Hsia, O.; Hinterndorfer, M.; Cowan, A. D.; Iso, K.; Ishida, T.; Sundaramoorthy, R.; Nakasone, M. A.; Imrichova, H.; Schätz, C.; Rukavina, A.; Husnjak, K.; Wegner, M.; Correa-Sáez, A.; Craigon, C.; Casement, R.; Maniaci, C.; Testa, A.; Kaulich, M.; Dikic, I.; Winter, G. E.; Ciulli, A. Targeted Protein Degradation via Intramolecular Bivalent Glues. Nature, 2024, 627(8002), 204–211. doi: 10.1038/s41586-024-07089-6
- Medina, S.; Miller, M. Synthetic Colonic Mucus Enables the Development of Modular Microbiome Organoids. Research Square, 2023. doi: 10.21203/rs.3.rs-3164407/v1
Cy® is a trademark of Cytiva.
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