Azide-PEG4-hydrazide

Cat. # Quantity Price Lead time
4697-100mg 100 mg $248 in stock
4697-500mg 500 mg $791 in stock
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Azide-PEG6-hydrazide is a heterobifunctional crosslinker with a hydrazide group, alkyne-reactive azide group, and a PEG4 hydrophilic linker.

The hydrazide group is used to attach the terminal azide group to a carbonyl group of aldehydes and ketones. Carbonyl groups are encountered in proteins subjected to oxidative stress. Many small natural molecules are also carbonyl compounds. Most saccharides and RNAs contain 1,2-diol fragments, which can be oxidized with periodate to aldehydes, which in turn react with hydrazides.

The azide group can undergo click chemistry reactions with alkyne, BCN, or DBCO to form a stable triazole linkage.

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Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

General properties

Appearance: white-yellow solid
Molecular weight: 341.80
CAS number: 2170240-96-5
Molecular formula: C11H24ClN5O5
Solubility: Methylene chloride, acetonitrile, DMF, DMSO, THF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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