sulfo-Cyanine5.5 carboxylic acid

Cat. # Quantity Price Lead time
17390 1 mg $125 in stock
27390 5 mg $325 in stock
47390 25 mg $850 in stock
57390 50 mg $1490 in stock
67390 100 mg $1990 in stock
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sulfo-Cyanine5.5 (analog of Cy5.5®) is a water-soluble, far-red emitting fluorophore. Due to four sulfo groups, the dye possesses a negative charge in neutral pH, and very high hydrophilicity. As a cyanine dye, sulfo-Cyanine5.5 shows a very low dependence of the fluorescence on pH, and a very high extinction coefficient.

This product is a free non-activated carboxylic acid that can be used for calibration and as a non-reactive control.

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 absorption and emission spectra

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sulfo-Cyanine5.5 amine

sulfo-Cyanine5.5 is a far-red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. This is an amine derivative that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling.

AF 555 carboxylic acid

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General properties

Appearance: dark blue solid
Molecular weight: 1017.31
CAS number: 2183440-68-6 (inner salt)
Molecular formula: C40H39K3N2O14S4
Solubility: Well soluble in water, DMF, DMSO (0.39 M = 400 g/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

Product citations

  1. Shik, A. V.; Sobolev, P. V.; Zubritskaya, Y. V.; Baytler, M. O.; Stepanova, I. A.; Chernyaev, A. P.; Borschegovskaya, P. Yu.; Zolotov, S. A.; Doroshenko, I. A.; Podrugina, T. A.; Bliznyuk, U. A.; Rodin, I. A.; Beklemishev, M. K. Rapid Testing of Irradiation Dose in Beef and Potatoes by Reaction-Based Optical Sensing Technique. Journal of Food Composition and Analysis, 2024, 127, 105946. doi: 10.1016/j.jfca.2023.105946
  2. Ko, H. S.; Yang, D. H.; Kim, A.; Wie, J. H.; Kim, S. H.; Jeong, G.-J.; Hyun, H.; Shin, J. C.; Chun, H. J. Visible Light-Curable Methacrylated Glycol Chitosan Hydrogel Patches for Prenatal Closure of Fetal Myelomeningocele. Carbohydrate Polymers, 2023, 311, 120620. doi: 10.1016/j.carbpol.2023.120620
  3. Park, J. Y.; You, S. J.; Park, K.; Song, Y. J.; Park, J. S.; Yang, D. H.; Kim, J. K.; Chun, H. J.; Khang, G. Cyclic RGDfK- and Sulfo-Cy5.5-Functionalized MPEG-PCL Theranostic Nanosystems for Hepatocellular Carcinoma. Journal of Industrial and Engineering Chemistry, 2021, 99, 204–213. doi: 10.1016/j.jiec.2021.04.023
  4. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
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