Cyanine7.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 16020 | 1 mg |
$125
|
in stock | |
| 26020 | 5 mg |
$260
|
in stock | |
| 46020 | 25 mg |
$510
|
in stock | |
| 56020 | 50 mg |
$895
|
in stock | |
| 66020 | 100 mg |
$1490
|
in stock |
Cyanine7.5 is a NIR dye with very long-wave emission. This product is amine-reactive derivative of this fluorophore.
Near infrared radiation readily penetrates tissues and can be used for imaging applications in vivo.
This product can be used for the labeling of various biomolecules containing amine groups, such as proteins and peptides, to track their distribution in organism in vivo by NIR imaging.
Increased rigidity of central polymethyne moiety allows to increase quantum yield by 20% compared to parent structure of Cy7.5® NHS.
Cy7.5 absorbance and emission spectra
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Alkyne hydrazide
Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.Copper(II)-TBTA complex
A catalyst for click reaction. A stable copper(II) complex which must be converted to monovalent copper(I) in situ using reducing agents. The complex can be used to prepare a reaction buffer of any composition.BDP® TMR NHS ester
Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.General properties
| Appearance: | green powder |
| Mass spec M+ increment: | 630.4 |
| Molecular weight: | 833.76 |
| CAS number: | 2708152-94-5 |
| Molecular formula: | C49H52N3BF4O4 |
| IUPAC name: | 1H-Benz[e]indolium, 2-[2-[3-[2-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 788 |
| ε, L⋅mol−1⋅cm−1: | 223000 |
| Emission maximum, nm: | 808 |
| Fluorescence quantum yield: | 0.10 |
Product citations
- Xu, H.; Yu, P.; Bandari, R.P.; Smith, C.J.; Aro, M.R.; Singh, A.; Ma, L. Bimodal MRI/Fluorescence Nanoparticle Imaging Contrast Agent Targeting Prostate Cancer. Nanomaterials, 2024, 14(14), 1177. doi: 10.3390/nano14141177
- Chang, C.; Liu, H.; Li, X.; Song, D.; Liu, Y.; Lu, C.; Zhen, Y.; Chen, Y.; Xu, J.; Li, W.; Jia, X.; Chen, Z.; Chen, R. Combined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model. International Journal of Nanomedicine, 2024, 19, 1205-1224. doi: 10.2147/ijn.s442761
- Nie, Q.; Li, C.; Wang, Y.; Hu, Y.; Pu, W.; Zhang, Q.; Cai, J.; Lin, Y.; Li, G.; Wang, C.; Li, L.; Dou, Y.; Zhang, J. Pathologically Triggered in Situ Aggregation of Nanoparticles for Inflammation-Targeting Amplification and Therapeutic Potentiation. Acta Pharmaceutica Sinica B, 2023, 13(1), 390–409. doi: 10.1016/j.apsb.2022.07.013
- Tang, M.; Chen, B.; Xia, H.; Pan, M.; Zhao, R.; Zhou, J.; Yin, Q.; Wan, F.; Yan, Y.; Fu, C.; Zhong, L.; Zhang, Q.; Wang, Y. pH-gated nanoparticles selectively regulate lysosomal function of tumour-associated macrophages for cancer immunotherapy. Nature Communications, 2023, 14, 5888. doi: 10.1038/s41467-023-41592-0
Cy® is a trademark of GE Healthcare.
Short link - lumiprobe.com/sh/p/P
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