sulfo-Cyanine3 maleimide

Cat. # Quantity Price Lead time
11380 1 mg
$93.99
in stock
21380 5 mg
$329.90
in stock
41380 25 mg
$829.90
in stock
51380 50 mg
$1299.00
in stock
61380 100 mg
$2099.00
in stock
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sulfo-Cyanine3 maleimide is a water-soluble, thiol-reactive dye for labeling. This is an analog of Cy3® maleimide.

This product is recommended for labeling antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require organic co-solvent.

A non-sulfonated Cyanine3 maleimide is available.

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

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General properties

Appearance: red powder
Molecular weight: 776.96
CAS number: 1656990-68-9
Molecular formula: C36H41KN4O9S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt, potassium salt
Solubility: soluble in water (0.39 M = 30 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

Product citations

  1. Liang, J.; Azubel, M.; Wang, G.; Nie, Y.; Kornberg, R. D.; Beel, A. J.; Mattei, P.-J. A Universal Method for the Purification of C2H2 Zinc Finger Arrays. PLOS ONE, 2025, 20(2), e0318295. doi: 10.1371/journal.pone.0318295
  2. Kartseva, M. E.; Kravchinskiy, D. M.; Morozov, V. N.; Staltsov, M. S.; Kuzmin, V. A.; Rudoy, V. M.; Dement’eva, O. V. Plasmonic Core/Shell Nanoparticles with Grafted Fluorophore: Synthesis and Emission Control. Optical Materials, 2025, 159, 116674. doi: 10.1016/j.optmat.2025.116674
  3. Hei, Y.; Wang, B.; He, Y.; Wang, W.; Xue, Y.; Chen, C. Photostability of Organic Fluorophore Influenced by Adjacent Amino Acid Residues. Commun Chem, 2025, 8(1), 262. doi: 10.1038/s42004-025-01661-5
  4. Damm, A.; Paik, S.-J.; Sadhu, R.K.; Di-Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Lévy, D.; Bassereau, P. Mechanosensitivity of an ABC Membrane Transporter Revealed by Single Molecule FRET and Activity Measurement. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.24.577054
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