sulfo-Cyanine3 maleimide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 11380 | 1 mg | $115 | in stock | |
| 21380 | 5 mg | $290 | in stock | |
| 41380 | 25 mg |
$695
|
in stock | |
| 51380 | 50 mg |
$1190
|
in stock | |
| 61380 | 100 mg |
$1990
|
in stock |
sulfo-Cyanine3 maleimide is a water-soluble, thiol-reactive dye for labeling. This is an analog of Cy3® maleimide.
This product is recommended for labeling antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require organic co-solvent.
A non-sulfonated Cyanine3 maleimide is available.
Sulfo-Cyanine3 maleimide
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General properties
| Appearance: | red powder |
| Molecular weight: | 776.96 |
| CAS number: | 1656990-68-9 |
| Molecular formula: | C36H41KN4O9S2 |
| IUPAC name: | 3H-Indolium, 2-[3-[1-[6-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-5-sulfo-, inner salt, potassium salt |
| Solubility: | soluble in water (0.39 M = 30 g/L), DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95+%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 548 |
| ε, L⋅mol−1⋅cm−1: | 162000 |
| Emission maximum, nm: | 563 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.03 |
| CF280: | 0.06 |
Product citations
- Damm, A.; Paik, S.-J.; Sadhu, R.K.; Di-Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Lévy, D.; Bassereau, P. Mechanosensitivity of an ABC Membrane Transporter Revealed by Single Molecule FRET and Activity Measurement. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.24.577054
- Proksch, J.; Dal Colle, M. C. S.; Heinz, F.; Schmidt, R. F.; Gottwald, J.; Delbianco, M.; Keller, B. G.; Gradzielski, M.; Alexiev, U.; Koksch, B. Impact of Glycan Nature on Structure and Viscoelastic Properties of Glycopeptide Hydrogels. Journal of Peptide Science, 2024, 30(8), e3599. doi: 10.1002/psc.3599
- Moochickal Assainar, B.; Ragunathan, K.; Baldridge, R.D. Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD. Nature Communications, 2024, 15, 1340. doi: 10.1038/s41467-024-45541-3
- Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
Cy® is a trademark of GE Healthcare.
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