Amino-11-ddUTP

Triphosphates PCR and qPCR

Cat. #	Quantity	Price	Lead time
A5040	200 nmol	$190	in stock
15040	1 umol	$549	in stock
25040	5 umol	$1590	in stock
45040	25 umol	$3975	in stock

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Amino-11-ddUTP is a terminator triphosphate for enzymatic end-labeling of DNA. The nucleotide is incorporated by Taq DNA polymerase, Sequenase, Klenow fragment. Subsequent reaction of amino-terminated DNA with activated esters can be used for the end-labeling of DNA.

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General properties

Appearance:	colorless solid
Molecular weight:	960.44
CAS number:	439077-17-5 (without cation and water of crystallization)
Molecular formula:	C₁₈H₆₂Li₃N₄O₃₂P₃
Solubility:	good in water
Quality control:	NMR ¹H and ³¹P, HPLC-MS (99+%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light and excessive freeze-thaw cycles.
MSDS:	Download
	Product specifications

Product citations

Paul, S.; Arias, M.A.; Wen, L.; Liao, S.E.; Zhang, J.; Wang, X.; Regev, O.; Fei, J. RNA molecules display distinctive organization at nuclear speckles. iScience, 2024, 27(5), 109603. doi: 10.1016/j.isci.2024.109603
Wu, J.; Xiao, Y.; Liu, Y.; Wen, L.; Jin, C.; Liu, S.; Paul, S.; He, C.; Regev, O.; Fei, J. Dynamics of RNA Localization to Nuclear Speckles Are Connected to Splicing Efficiency. Science Advances, 2024, 10(42), eadp7727. doi: 10.1126/sciadv.adp7727
Chen, R.; Stainier, W.; Dufourt, J.; Lagha, M.; Lehmann, R. Direct observation of translational activation by a ribonucleoprotein granule. Nature cell biology, 2024, 26(8), 1322-1335. doi: 10.1038/s41556-024-01452-5
Dave, P.; Roth, G.; Griesbach, E.; Mateju, D.; Hochstoeger, T.; Chao, J.A. Single-molecule imaging reveals translation-dependent destabilization of mRNAs. Molecular Cell, 2023, 83(4), 589-606.e6. doi: 10.1016/j.molcel.2023.01.013

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This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.