Biotin-PEG3-azide
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
C3730 | 10 mg | $125 | in stock | |
D3730 | 25 mg | $220 | in stock | |
E3730 | 50 mg | $325 | in stock | |
F3730 | 100 mg | $450 | in stock | |
K3730 | 1 g | $1420 | in stock |
Biotin-PEG3-azide is a click chemistry biotinylation tool. This reagent allows the labeling of alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin via copper-catalyzed or copper-free click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection.
This structure of biotin azide features a long hydrophilic PEG3 linker that separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker also enhances aqueous solubility to facilitate conjugation.
The azide can be conjugated with various molecules using our recommended protocol.
Customers also purchased with this product
Cyanine7.5 azide
Long-wavelength NIR fluorescent dye azide for click chemistry.Biotin phosphoramidite (hydroxyprolinol)
Biotin phosphoramidite reagent for the synthesis of biotinylated oligos. Contains a dimethyoxytrityl group.get free express delivery
Cyanine7 DBCO
NIR fluorescent dye functionalized with cyclooctyne moiety for copper free click chemistry conjugation with azides.General properties
Appearance: | colorless solid |
Molecular weight: | 400.50 |
CAS number: | 1910803-72-3 |
Molecular formula: | C16H28N6O4S |
Solubility: | soluble in DMF, DMSO, moderately soluble in water |
Quality control: | NMR 1H (95%) and 13C, TLC, functional testing |
Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. |
MSDS: | Download |
Product specifications |
Product citations
- Liang, J.; Han, J.; Gao, X.; Jia, H.; Li, R.; Tse, E. C. M.; Li, Y. Clickable APEX2 Probes for Enhanced RNA Proximity Labeling in Live Cells. Anal. Chem., 2024, 96(2), 685–693. doi: 10.1021/acs.analchem.3c03614
- Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L. Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; Strašák, T. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences, 2022, 23(4), 2114. doi: 10.3390/ijms23042114
- Shen, J.Z.; Qiu, Z.; Wu, Q.; Finlay, D.; Garcia, G.; Sun, D.; Rantala, J.; Barshop, W.; Hope, J.L.; Gimple, R.C.; Sangfelt, O.; Bradley, L.M.; Wohlschlegel, J.; Rich, J.N.; Spruck, C. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell, 2021, 184(2), 352–369.e23. doi: 10.1016/j.cell.2020.11.042
- Zeng, Q.; Deng, H.; Li, Y.; Fan, T.; Liu, Y.; Tang, S.; Wei, W.; Liu, X.; Guo, X.; Jiang, J.; Wang, Y.; Song, D. Berberine Directly Targets the NEK7 Protein to Block the NEK7–NLRP3 Interaction and Exert Anti-inflammatory Activity. Journal of Medicinal Chemistry, 2021, 64(1), 768–781. doi: 10.1021/acs.jmedchem.0c01743