Cyanine7 alkyne

Cyanine7 Alkynes Click chemistry Near infrared (NIR) imaging
Cat. # Quantity Price Lead time
A50B0 1 mg $125 in stock
B50B0 5 mg $260 in stock
C50B0 10 mg $325 in stock
D50B0 25 mg $510 5 days
E50B0 50 mg $895 in stock
F50B0 100 mg $1490 in stock
Bulk inquiry
Found better price? Let us know and we will propose the way forward!

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7®. The alkyne can be conjugated to a variety of azides via copper-catalyzed click chemistry.

The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

Cyanine7 alkyne, F50B0
Cyanine7 alkyne, F50B0
Cyanine7 alkyne, F50B0
Structure of Cyanine7 alkyne
Download in
ChemDraw format

Absorbance and emission spectra of Cyanine7

Absorbance and emission spectra of Cyanine7

Recommended protocol

Calculator

Customers also purchased with this product

FAM azide, 5-isomer

FAM (fluorescein) azide for сlick chemistry labeling, pure 5-isomer.

Cyanine5.5 tetrazine

A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.

FAM-11-UTP, 6-isomer

6-FAM-uridine triphosphate for non-radioactive enzymatic RNA labeling during in vitro transcription.

General properties

Appearance: green powder
Mass spec M+ increment: 586.4
Molecular weight: 622.28
CAS number: 1998119-13-3 (chloride), 1954687-62-7
Molecular formula: C40H48ClN3O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Product citations

  1. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  2. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
  3. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  4. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
Show more (2)
Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
Short link - lumiprobe.com/sh/p/25
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.