LumiCell CDr20 Microglia Stain
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 3570-50ug | 50 ug | $50 | in stock | |
| 3570-500ug | 500 ug | $350 | in stock |
CDr20 (Cell Designation red 20) is a high-performance fluorogenic chemical probe for labeling microglia in both cell cultures and live brains. CDr20 is a substrate of microglia-specific UDP-glucuronosyltransferase Ugt1a7c. The glucuronidation of CDr20 by Ugt1a7c produces bright red fluorescence in microglial cells coinciding with the expression of markers P2ry12, Csf1r, Cx3cr1, and Iba-1 [1].
CDr20 could be a valuable tool for identifying and visualizing microglia in neural disorder studies both in vitro and in vivo and for CDr20-based fluorescent-activated microglial cell sorting (FACS).
[1] Kim B. et al. Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate. Angew. Chem. Int. Ed. Engl. 2019. 58(24). 7972-7976.
Product in action
BV2 microglial cells stained with LumiCell CDr20 Microglia Stain (3570-x)
Absorption and emission spectra of CDr20 Microglia Stain
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| Appearance: | greenish black crystals |
| Molecular weight: | 354.17 |
| CAS number: | 1201643-01-7 |
| Molecular formula: | C19H17BF2N2O2 |
| Solubility: | DMSO |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 562 |
| ε, L⋅mol−1⋅cm−1: | 97500 |
| Emission maximum, nm: | 581 |
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