Cyanine5 tetrazine

Cat. # Quantity Price Lead time
130E0 1 mg
$125
in stock
230E0 5 mg
$260
in stock
430E0 25 mg
$510
in stock
530E0 50 mg
$895
in stock
630E0 100 mg
$1490
in stock
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Tetrazine-cyclooctene (TCO) ligation is one of the fastest bioconjugation reactions known to date. In order to use it for fluorescent labeling, a fluorescent reporter molecule bearing one of the reacting groups is necessary.

Cyanine5 tetrazine is a molecule bearing Cyanine5 fluorophore, and tetrazine moiety. Cyanine5 is a very popular fluorophore compatible with numerous instruments.

Absorption and emission spectra of Cyanine5

Absorption and emission spectra of Cyanine5

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DBCO-NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

sulfo-Cyanine5 DBCO

Water-soluble cycloalkyne for copper-free click chemistry reaction with azides. A derivative of sulfo-Cyanine5.

General properties

Appearance: dark blue solid
Mass spec M+ increment: 637.4
Molecular weight: 811.84
Molecular formula: C42H48N7F6OP
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

Product citations

  1. Santiana, J.J. ; Sawant, S.S.; Gomez, N.; Rouge, J. L. Multi-Layered Stimuli Responsive DNA Micelles for the Stepwise Controlled Release of Small Molecules. Journal of Materials Chemistry B, 2022, 10(37), 7518–7526. doi: 10.1039/D1TB02722K
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