sulfo-Cyanine7.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 16320 | 1 mg |
$179.90
|
in stock | |
| 26320 | 5 mg |
$469.90
|
in stock | |
| 46320 | 25 mg |
$949.90
|
in stock | |
| 56320 | 50 mg |
$1599.00
|
in stock | |
| 66320 | 100 mg |
$2899.00
|
in stock |
sulfo-Cyanine7.5 is a near-infrared water-soluble and hydrophilic dye for the NIR imaging applications. The structure and spectra of the dye resemble indocyanine green (ICG) which has been approved for use in humans for years. However, unlike ICG, sulfo-Cyanine7.5 contains a trimethylene bridge that increases its quantum yield compared to ICG and has a linker arm for its attachment to proteins, peptides, and other molecules. This derivative is an NHS ester for the modification of amine groups.
Absorption and emission spectra of sulfo-Cyanine7.5
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General properties
| Appearance: | dark green solid |
| Mass spec M+ increment: | 950.2 |
| Molecular weight: | 1180.47 |
| Molecular formula: | C49H48N3K3O16S4 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 778 |
| ε, L⋅mol−1⋅cm−1: | 222000 |
| Emission maximum, nm: | 797 |
| Fluorescence quantum yield: | 0.21 |
| CF260: | 0.09 |
| CF280: | 0.09 |
Product citations
- Shevtsov, M.; Yudintceva, N.; Bobkov, D.; Likhomanova, R.; Nechaeva, A.; Mikhailova, E.; Oganesyan, E.; Fedorov, V.; Kurkin, A.; Lukacheva, A.; Fofanov, G.; Kim, A.; Fedorov, E.; Sitovskaya, D.; Ulitin, A.; Mikhailova, N.; Anufriev, I.; Istomina, M.; Murashko, E.; Kessenikh, E.; Aksenov, N.; Vakhitova, Y.; Samochernykh, K.; Pitkin, E.; Shlyakhto, E.; Combs, S. E. RAS70 Peptide Targets Multiforme Glioblastoma by Binding to the Plasma Membrane Heat Shock Protein HSP70. Front. Oncol., 2025, 15. doi: 10.3389/fonc.2025.1543657
- Colville, M.J.; Huang, L.-T.; Schmidt, S.; Chen, K.; Vishwanath, K.; Su, J.; Williams, R.M.; Bonassar, L.J.; Reesink, H.L.; Paszek, M.J. Recombinant manufacturing of multispecies biolubricants. bioRxiv, 2024, preprint. doi: 10.1101/2024.05.05.592580
- Khadria, A.; Paavola, C.D.; Maslov, K.; Brown-Augsburger, P.L.; Grealish, P.F.; Lozano, E.; Blankenship, R.L.; Cao, R.; Shi, J.; Beals, J.M.; Oladipupo, S.S.; Wang, L.V. Photoacoustic imaging of the dynamics of a dye-labeled IgG4 monoclonal antibody in subcutaneous tissue reveals a transient decrease in murine blood oxygenation under anesthesia. Journal of Biomedical Optics, 2023, 28(11), 116002. doi: 10.1117/1.jbo.28.11.116002
- Shevchuk, A. I.; Svinko, V. O.; Smirnov, A. N.; Solovyeva, E. V. SERS Study of Cyanine Dyes: Optimization of Metal Core and Molecular Label Choice for Plasmonic Nanotags. Dyes and Pigments, 2023, 216, 111329. doi: 10.1016/j.dyepig.2023.111329.
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