sulfo-Cyanine3.5 NHS ester

NHS esters sulfo-Cyanine3.5

Cat. #	Quantity	Price	Lead time
12320	1 mg	$125	in stock
22320	5 mg	$325	in stock
42320	25 mg	$850	in stock
52320	50 mg	$1490	in stock
62320	100 mg	$1990	in stock

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Cyanine3.5 is a fluorescent dye with absorption and emission intermediate between Cyanine3 and Cyanine5. The sulfonated version contains four sulfo groups, which ensure high solubility and hydrophilicity of the fluorophore and labeled conjugates.

The NHS ester reactive group allows labeling of primary and secondary amine groups.

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Absorption and emission spectra of sulfo-Cyanine3.5

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General properties

Appearance:	deep purple powder
Molecular weight:	1088.33
CAS number:	2231670-91-8 (without cation)
Molecular formula:	C₄₂H₄₀N₃K₃O₁₆S₄
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	576
ε, L⋅mol⁻¹⋅cm⁻¹:	139000
Emission maximum, nm:	603
Fluorescence quantum yield:	0.11
CF₂₆₀:	0.16
CF₂₈₀:	0.17

Product citations

McGuire, K.; He, S.; Gracie, J.; Bryson, C.; Zheng, D.; Clark, A.W.; Koehnke, J.; France, D.J.; Nau, W.M.; Lee, T.-C.; Peveler, W.J. Supramolecular Click Chemistry for Surface Modification of Quantum Dots Mediated by Cucurbit[7]uril. ACS nano, 2023, 17(21), 21585-21594. doi: 10.1021/acsnano.3c06601
Shramova, E.; Proshkina, G.; Shipunova, V.; Ryabova, A.; Kamyshinsky, R.; Konevega, A.; Schulga, A.; Konovalova, E.; Telegin, G.; Deyev, S. Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape. Cancers, 2020, 12(10), 3014. doi: 10.3390/cancers12103014

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.