Cyanine3 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 11020 | 1 mg |
$129.90
|
in stock | |
| 21020 | 5 mg |
$169.90
|
in stock | |
| 41020 | 25 mg |
$539.90
|
in stock | |
| 51020 | 50 mg |
$999.00
|
in stock | |
| 61020 | 100 mg |
$1699.00
|
in stock | |
| 81020 | 1 g |
please inquire
|
in stock |
Cyanine3 NHS ester is a reactive dye for the labeling of amino-groups in biomolecules, an analog of Cy3® NHS ester. This reagent is ideal for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. For delicate proteins consider using water-soluble sulfo-Cyanine3 NHS ester which does not require use of any co-solvent.
Cyanine3 NHS ester is a replacement for NHS esters of Cy3® and DyLight 549.
Absorption and emission spectra of Cyanine3
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General properties
| Appearance: | red powder |
| Mass spec M+ increment: | 439.5 |
| Molecular weight: | 641.5 |
| CAS number: | 2632339-91-2 |
| Molecular formula: | C34H40N3BF4O4 |
| IUPAC name: | 3H-Indolium, 2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3,3-dimethyl-, tetrafluoroborate |
| Solubility: | poorly soluble in water (2.3 mM = 1.5 g/L), soluble in organic solvents (DMF, DMSO, dichloromethane) |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 555 |
| ε, L⋅mol−1⋅cm−1: | 150000 |
| Emission maximum, nm: | 570 |
| Fluorescence quantum yield: | 0.31 |
| CF260: | 0.04 |
| CF280: | 0.09 |
Product citations
- Oh, H. J.; Lee, Y.; Hwang, H.; Hong, K.; Choi, H.; Kang, J. Y.; Jung, Y. Size-Controlled Assembly of Phase Separated Protein Condensates with Interfacial Protein Cages. Nat Commun, 2025, 16(1), 1009. doi: 10.1038/s41467-025-56391-y
- Raik, S.; Aseyev, V.; Vuorimaa-Laukkanen, E.; Tavakoli, S.; Yetgin, C.; Laaksonen, T.; Urtti, A. Chitosan - Hyaluronate Based Polyplexes for the Delivery of Oligonucleotides: Structural Properties and Intravitreal Mobility. Carbohydrate Polymers, 2025, 366, 123920. doi: 10.1016/j.carbpol.2025.123920
- Bai, X.; Xu, L.; Wang, Z.; Zhuang, X.; Ning, J.; Sun, Y.; Wang, H.; Guo, Y.; Xu, Y.; Guo, J.; Chen, S.; Pan, L. Computational-Aided Rational Mutation Design of Pertuzumab to Overcome Active HER2 Mutation S310F through Antibody–Drug Conjugates. Proc. Natl. Acad. Sci. U.S.A., 2025, 122(1), e2413686122. doi: 10.1073/pnas.2413686122
- Eskilson, O.; Wiman, E.; Reustle, N.; Langwagen, J.; Sotra, Z.; Svärd, A.; Selegård, R.; Baş, Y.; Berglund, L.; Oksman, K.; Bengtsson, T.; Junker, J. P. E.; Khalaf, H.; Aili, D. Nanocellulose Wound Dressings with Integrated Protease Sensors for Detection of Wound Pathogens. ACS Sens, 2025, 10(6), 3953–3963. doi: 10.1021/acssensors.4c03428
Cy® is a trademark of Cytiva.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
Short link - lumiprobe.com/sh/p/d
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