sulfo-Cyanine5 tetrazine

Cat. # Quantity Price Lead time
133E0 1 mg
$125
in stock
233E0 5 mg
$325
in stock
333E0 10 mg
$470
in stock
433E0 25 mg
$850
in stock
533E0 50 mg
$1490
in stock
633E0 100 mg
$1990
in stock
Found better price? Let us know and we will propose the way forward!

TCO (tetrazine – trans-cyclooctene) ligation is one of the fastest reactions used for bioconjugation. It is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefins.

sulfo-Cyanine5 tetrazine is a fluorophore derivative bearing a tetrazine group for the TCO-ligation-based labeling.

This reagent possesses good aqueous solubility and stability in biological environments.

Absorption and emission spectra of Sulfo-Cyanine5

Absorption and emission spectra of Sulfo-Cyanine5

Customers also purchased with this product

AF 488 DBCO

Dibenzocyclooctyne (DBCO, ADIBO) containing the green fluorophore AF 488 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples. Pure 5-isomer.

BDP® 558/568 carboxylic acid

BDP 558/568 is a borondipyrromethene dye with yellow emission. The dye as a carboxylic acid can be used in peptide synthesis (after appropriate activation of the carboxylic group).
Add this product to your cart and
get free express delivery

Cyanine5 azide

Cyanine5 azide is a reagent for click chemistry labeling with Cyanine5, a popular fluorescent dye.
Add this product to your cart and
get free express delivery

General properties

Appearance: dark blue solid
Molecular weight: 864.09
Molecular formula: C42H46KN7O7S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Comeo, E.; Goulding, J.; Lin, C.-Y.; Groenen, M.; Woolard, J.; Kindon, N. D.; Harwood, C. R.; Platt, S.; Briddon, S. J.; Kilpatrick, L. E.; Scammells, P. J.; Hill, S. J.; Kellam, B. Ligand-Directed Labeling of the Adenosine A1 Receptor in Living Cells. J. Med. Chem., 2024, 67(14), 12099–12117. doi: 10.1021/acs.jmedchem.4c00835
  2. Kerr, M. D.; McBride, D. A.; Johnson, W. T.; Chumber, A. K.; Najibi, A. J.; Seo, B. R.; Stafford, A. G.; Scadden, D. T.; Mooney, D. J.; Shah, N. J. Immune-Responsive Biodegradable Scaffolds for Enhancing Neutrophil Regeneration. Bioengineering & Translational Medicine, 2023, 8(1), e10309. doi: 10.1002/btm2.10309
  3. Kerr, M.D.; Johnson, W.T.; McBride, D.A.; Chumber, A.K.; Shah, N.J. Biodegradable scaffolds for enhancing vaccine delivery. Bioengineering & translational medicine, 2023, 8(6), e10591. doi: 10.1002/btm2.10591
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.