Cyanine3B tetrazine

Tetrazines Copper-free click chemistry Cyanine3B

Cat. #	Quantity	Price	Lead time
193E0	1 mg	$348	in stock
293E0	5 mg	$737	in stock
493E0	25 mg	$1950	in stock

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Cyanine3B methyltetrazine derivative for Inverse electron demand Diels-Alder (IEDDA) conjugation with strained olefins and terminal alkenes. IEDDA is the fastest cycloaddition reaction among click reactions known. Methyltetrazines have optimal physiological pH stability while maintaining extremely high reactivity towards cyclooctenes. Tetrazines also react with some strained cycloalkynes.

Cyanine3B is a yellow-emitting cyanine dye. It is an improved version of the Cyanine3 fluorophore, with significantly higher fluorescence quantum yield and photostability.

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Absorption and emission spectra of Cyanine3B

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General properties

Appearance:	red powder
Molecular weight:	743.89
Molecular formula:	C₄₁H₄₁N₇O₅S
Solubility:	good in DCM, DMSO, DMF
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	559
ε, L⋅mol⁻¹⋅cm⁻¹:	121000
Emission maximum, nm:	571
Fluorescence quantum yield:	0.68
CF₂₆₀:	0.044
CF₂₈₀:	0.077

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.