Cyanine5.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 17020 | 1 mg | $125 | in stock | |
| 27020 | 5 mg | $260 | in stock | |
| 47020 | 25 mg |
$510
|
in stock | |
| 57020 | 50 mg |
$895
|
in stock | |
| 67020 | 100 mg |
$1490
|
in stock |
Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester.
Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments.
This reagent can replace NHS esters of Cy5.5® and DyLight 680.
Cy5.5 absorbance and emission spectra
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General properties
| Appearance: | dark blue to violet solid |
| Molecular weight: | 767.66 |
| CAS number: | 2375105-86-3 |
| Molecular formula: | C44H46N3BF4O4 |
| IUPAC name: | 1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 684 |
| ε, L⋅mol−1⋅cm−1: | 198000 |
| Emission maximum, nm: | 710 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.07 |
| CF280: | 0.03 |
Product citations
- Yun, W.S.; Yang, W.; Shim, M.K.; Song, S.; Choi, J.; Kim, J.; Kim, J.; Moon, Y.; Jo, S.H.; Lim, D.-K.; Kim, K. Accurately controlled tumor temperature with silica-coated gold nanorods for optimal immune checkpoint blockade therapy. Biomaterials Research, 2024, 28, 0024. doi: 10.34133/bmr.0024
- Liu, Q.; Wang, C.; Zhu, M.; Liu, J.; Duan, Q.; Midgley, A.C.; Liu, R.; Jiang, B.; Kong, D.; Chen, Q.; Zhuang, J.; Huang, X. Self‐Assembly of Heterogeneous Ferritin Nanocages for Tumor Uptake and Penetration. Advanced Science, 2024, 11(17), 2309271. doi: 10.1002/advs.202309271
- Han, G.; Kim, H.; Jang, H.; Kim, E.S.; Kim, S.H.; Yang, Y. Oral TNF-α siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease. Bioactive Materials, 2024, 34, 138-149. doi: 10.1016/j.bioactmat.2023.12.010
- Halim, A.; Al-Qadi, N.; Kenyon, E.; Conner, K.N.; Mondal, S.K.; Medarova, Z.; Moore, A. Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties. Oncotarget, 2024, 15, 591-606. doi: 10.18632/oncotarget.28641
Cy® is a trademark of Cytiva.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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