BDP® FL maleimide

BDP® FL Maleimides Fluorescence polarization
Cat. # Quantity Price Lead time
11480 1 mg $125 in stock
21480 5 mg $260 5 days
41480 25 mg $510 in stock
51480 50 mg $895 in stock
61480 100 mg $1490 in stock
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Thiol reactive BDP FL maleimide is a reactive dye for protein labeling.

BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar to fluorescein (FAM). However, this dye exhibits very high photostability. It is non-charged, and has low molecular weight. Its brightness is similar to fluorescein, R110 and xanthene dye derivatives.

This fluorophore is ideal for fluorescent microscopy and many other applications. The fluorophore can substitute fluorescein for almost any application, and it is compatible with any FAM-capable fluorescent instrumentation.

BDP FL maleimide, 61480
BDP FL maleimide, 61480
Photo of BDP FL solution
Structure of BODIPY FL maleimide
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Absorption and emission spectra of BDP FL

Absorption and emission spectra of BDP FL

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AmdU (5-Azidomethyl-2'-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.

General properties

Appearance: orange solid
Mass spec M+ increment: 414.1
Molecular weight: 414.21
CAS number: 773859-49-7
Molecular formula: C20H21BF2N4O3
Solubility: Good in organic solvents (DMF, DMSO), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

Product citations

  1. Chandler, T.; Guo, M.; Su, Y.; Chen, J.; Wu, Y.; Liu, J.; Agashe, A.; Fischer, R. S.; Mehta, S. B.; Kumar, A.; Baskin, T. I.; Jaumouillé, V.; Liu, H.; Swaminathan, V.; Nain, A. S.; Oldenbourg, R.; La Riviere, P. J.; Shroff, H. Volumetric Imaging of the 3D Orientation of Cellular Structures with a Polarized Fluorescence Light-Sheet Microscope. Proceedings of the National Academy of Sciences, 2025, 122(8), e2406679122. doi: 10.1073/pnas.2406679122
  2. Chandler, T.; Guo, M.; Su, Y.; Chen, J.; Wu, Y.; Liu, J.; Agashe, A.; Fischer, R.S.; Mehta, S.B.; Kumar, A.; Baskin, T.I.; Jamouillé, V.; Liu, H.; Swaminathan, V.; Nain, A.; Oldenbourg, R.; Riviére, P.L.; Shroff, H. Three-dimensional spatio-angular fluorescence microscopy with a polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM). bioRxiv, 2024, preprint. doi: 10.1101/2024.03.09.584243
  3. Gileva, A.; Trushina, D.; Yagolovich, A.; Gasparian, M.; Kurbanova, L.; Smirnov, I.; Burov, S.; Markvicheva, E. Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells. Nanomaterials, 2023, 13(5), 902. doi: 10.3390/nano13050902
  4. Marotta, N. P.; Ara, J.; Uemura, N.; Lougee, M. G.; Meymand, E. S.; Zhang, B.; Petersson, E. J.; Trojanowski, J. Q.; Lee, V. M.-Y. Alpha-Synuclein from Patient Lewy Bodies Exhibits Distinct Pathological Activity That Can Be Propagated in Vitro. Acta Neuropathologica Communications, 2021, 9(1), 188. doi: 10.1186/s40478-021-01288-2
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BDP® is a trademark of Lumiprobe
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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