EdU (5-Ethynyl-2'-deoxyuridine)
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
A0540 | 5 mg | – | in stock | |
10540 | 100 mg | $120 | in stock | |
20540 | 250 mg | $195 | in stock | |
30540 | 500 mg | $345 | in stock | |
40540 | 1 g | $590 | in stock | |
60540 | 5 g | please inquire | in stock |
EdU (5-ethynyl-2’-deoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. After EdU incorporation, DNA containing ethynyl groups can be ligated by click chemistry reaction with various dye azides. Fluorescent DNA can be detected with microscopy, or cells can be sorted with FACS.
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BTTAA ligand
BTTAA is the newest generation of water-soluble ligands for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity.General properties
Appearance: | light beige to light brown solid |
Molecular weight: | 252.22 |
CAS number: | 61135-33-9 |
Molecular formula: | C11H12N2O5 |
Solubility: | in water, DMSO |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
MSDS: | Download |
Product specifications |
Product citations
- Minutti, C.M.; Piot, C.; Pereira da Costa, M.; Chakravarty, P.; Rogers, N.; Huerga Encabo, H.; Cardoso, A.; Loong, J.; Bessou, G.; Mionnet, C.; Langhorne, J.; Bonnet, D.; Dalod, M.; Tomasello, E.; Reis e Sousa, C. Distinct ontogenetic lineages dictate cDC2 heterogeneity. Nature Immunology, 2024, 25, 448–461. doi: 10.1038/s41590-024-01745-9
- Dopeso, H.; Rodrigues, P.; Cartón-García, F.; Macaya, I.; Bilic, J.; Anguita, E.; Jing, L.; Brotons, B.; Vivancos, N.; Beà, L.; Sánchez-Martín, M.; Landolfi, S.; Hernandez-Losa, J.; Ramon y Cajal, S.; Nieto, R.; Vicario, M.; Farre, R.; Schwartz Jr, S.; van Ijzendoorn, S.C.D.; Kobayashi, K.; Martinez-Barriocanal, Á.; Arango, D. RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis. iScience, 2024, 27(4), 109400. doi: 10.1016/j.isci.2024.109400
- Alruwaili, M.M.; Zonneville, J.; Naranjo, M.N.; Serio, H.; Melendy, T.; Straubinger, R.M.; Gillard, B.; Foster, B.A.; Rajan, P.; Attwood, K.; Chatley, S.; Iyer, R.; Fountzilas, C.; Bakin, A.V. A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers. Cell Reports Medicine, 2024, 5(3), 101434. doi: 10.1016/j.xcrm.2024.101434
- Swan, J.; Szabó, Z.; Peters, J.; Kummu, O.; Kemppi, A.; Rahtu-Korpela, L.; Konzack, A.; Hakkola, J.; Pasternack, A.; Ritvos, O.; Kerkelä, R.; Magga, J. Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease. Biomedicine & Pharmacotherapy, 2024, 175, 116683. doi: 10.1016/j.biopha.2024.116683
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