ROX tetrazine, 5-isomer
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 112E0 | 1 mg | $110 | in stock | |
| 212E0 | 5 mg | $210 | in stock | |
| 412E0 | 25 mg |
$410
|
in stock | |
| 512E0 | 50 mg |
$695
|
in stock | |
| 612E0 | 100 mg |
$1190
|
in stock |
ROX tetrazine is a derivative of ROX (Rhodamine X, Rhodamine 101) dye, a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This compound contains tetrazine moiety that reacts with trans-cycloalkenes and other strained olefins in inverse electron demand Diels-Alder reaction (IEDDA). The reaction is very quick and specific. This reagent is a pure 5-isomer of ROX.
Absorption and emission spectra of ROX
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Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.General properties
| Appearance: | dark colored solid |
| Molecular weight: | 717.83 |
| Molecular formula: | C43H39N7O4 |
| Solubility: | good in DMSO, DMF, methanol, ethanol |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 570 |
| ε, L⋅mol−1⋅cm−1: | 93000 |
| Emission maximum, nm: | 591 |
| Fluorescence quantum yield: | 1.0 |
| CF260: | 0.62 |
| CF280: | 0.49 |
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