Cyanine3 carboxylic acid

Cat. # Quantity Price Lead time
11090 1 mg $110 in stock
21090 5 mg $210 in stock
41090 25 mg $410 in stock
51090 50 mg $695 in stock
61090 100 mg $1190 in stock
Found better price? Let us know and we will propose the way forward!

Free Cyanine3 carboxylic acid (Cy3® carboxylic acid analog), non-activated dye. Non-sulfonated reagent, with good solubility in organic solvents and limited aqueous solubility. The dye can be used as a non-reactive fluorophore for control experiments, and for calibration.

For coupling with amines, and labeling, consider using Cyanine3 NHS ester, or water-soluble sulfo-Cyanine3 NHS ester.

Cyanine3 absorbance and emission spectra

Cyanine3 absorbance and emission spectra

Customers also purchased with this product

DMSO (dimethyl sulfoxide), labeling grade

Pure dimethyl sulfoxide (DMSO) solvent with quality optimized for bioconjugation reactions.

Cyanine3B carboxylic acid

A Cyanine3B derivative with unactivated free carboxy group for use as a control, calibration, and conjugation after pre-activation.
Add this product to your cart and
get free express delivery

sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

General properties

Appearance: red powder
Molecular weight: 493.08
CAS number: 1361402-15-4 (inner salt), 1032678-01-5 (chloride), 1251915-29-3 (iodide)
Molecular formula: C30H37ClN2O2
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), poorly soluble in water (1.8 g/L = 4.0 mM)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

Product citations

  1. Herkert, E.K.; Lau, L.; Pons Lanau, R.; Garcia-Parajo, M.F. Hexagonal Plasmonic Arrays for High-Throughput Multicolor Single-Molecule Studies. ACS Applied Materials & Interfaces, 2024, 16(31), 41271-41280. doi: 10.1021/acsami.4c04744
  2. De Pauw, E.; Chen, Y.; De Keersmaecker, H.; De Coninck, E.; De Smet, L.; De Geest, B.; Braeckmans, K.; Vervaet, C.; Vanhoorne, V. Drying Behaviour and Visualization of Surfactants after Co-Spray Drying of Surfactant-Stabilized Aqueous Suspensions. International Journal of Pharmaceutics, 2023, 643, 123231. doi: 10.1016/j.ijpharm.2023.123231
  3. Xu, S.; Zhang, P.; Heing-Becker, I.; Zhang, J.; Tang, P.; Bej, R.; Bhatia, S.; Zhong, Y.; Haag, R. Dual Tumor- and Subcellular-Targeted Photodynamic Therapy Using Glucose-Functionalized MoS2 Nanoflakes for Multidrug-Resistant Tumor Ablation. Biomaterials, 2022, 290, 121844. doi: 10.1016/j.biomaterials.2022.121844
  4. Mattila, J. T.; Beaino, W.; White, A. G.; Nyiranshuti, L.; Maiello, P.; Tomko, J.; Frye, L. J.; Fillmore, D.; Scanga, C. A.; Lin, P. L.; Flynn, J. L.; Anderson, C. J. Retention of 64Cu-FLFLF, a Formyl Peptide Receptor 1-Specific PET Probe, Correlates with Macrophage and Neutrophil Abundance in Lung Granulomas from Cynomolgus Macaques. ACS Infect. Dis., 2021, 7(8), 2264–2276. doi: 10.1021/acsinfecdis.0c00826
Show more (8)
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.