Cyanine5.5 tetrazine

Cat. # Quantity Price Lead time
170E0 1 mg $125 in stock
270E0 5 mg $260 in stock
470E0 25 mg $510 in stock
570E0 50 mg $895 in stock
670E0 100 mg $1490 in stock
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Cyanine5.5 is a far red emitting dye for in vivo imaging and applications requiring low background. This Cyanine5.5 derivative contains tetrazine moiety that reacts with trans-cyclooctenes, cyclopropenes, and some strained cyclooctynes to form stable conjugates.

This labeling reaction is extremely fast and can be used in vivo.

Absorption and emission spectra of Cyanine5.5

Absorption and emission spectra of Cyanine5.5

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Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Alkyne-PEG3-amine

Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.

sulfo-Cyanine5.5 NHS ester

Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

General properties

Appearance: dark blue solid
Mass spec M+ increment: 737.4
Molecular weight: 911.96
Molecular formula: C50H52N7F6OP
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Dinesen, A.; Winther, A.; Wall, A.; Märcher, A.; Palmfeldt, J.; Chudasama, V.; Wengel, J.; Gothelf, K. V.; Baker, J. R.; Howard, K. A. Albumin Biomolecular Drug Designs Stabilized through Improved Thiol Conjugation and a Modular Locked Nucleic Acid Functionalized Assembly. Bioconjugate Chem., 2022, 33(2), 333–342. doi: 10.1021/acs.bioconjchem.1c00561
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