DusQ 3 CPG 500
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 1618-100mg | 100 mg | – | in stock | |
| 1618-1g | 1 g |
$990
|
in stock |
DusQ 3 is a dark quencher for far red and near infrared fluorophores, especially suitable for Cyanine5.5.
The dye can be attached to 3'-terminus of oligonucleotides by means of automated solid phase synthesis using this support. The dye is sensitive to nucleophilic reagents, and therefore must be carefully deprotected. We recommend the use of ultramild, phenoxyacetyl protected monomers. As an alternative, post-synthetic labeling using NHS ester of the quencher can be used.
Absorption spectrum of DusQ 3
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This universal support is intended for automated synthesis of oligonucleotides to accelerate the dephosphorylation process during deblocking. Pore size of 1000 Å is recommended for the synthesis of oligonucleotides up to 120 bases.DusQ 21 CPG 500
DusQ 21 is a quencher for dyes in red part of the spectrum, including Cyanine5 and Cyanine5.5.
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General properties
| Appearance: | dark blue beads |
| Quality control: | 1H NMR of bound reagent, coupling testing with HPLC-MS |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 657 |
| ε, L⋅mol−1⋅cm−1: | 45500 |
Oligo synthesis details
| Pore size, Å: | 500 |
| Typical loading, umol/g: | 50-80 |
| Coupling conditions: | standard, ultramild phosphoramidites |
| Cleavage conditions: | 2 h / rt, 30% aq. ammonia (ultramild protective groups) |
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