H-Met-AMC, сalpain substrate

Cat. # Quantity Price Lead time
4454-100mg 100 mg $145 in stock
4454-1g 1 g $695 in stock
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H-Met-AMC (L-methionine-7-amido-4-methylcoumarin) is a fluorogenic substrate for methionine aminopeptidase 2 (MetAP2) (Km=310 µM) and aminopeptidase N (Km=377 µM). This substrate is a useful tool for inhibitor screening and kinetic analysis.

H-Met-AMC has an excitation peak at 380 nm and emission at 460 nm. The following excitation/emission can also be used: 355,375/440,450.

General properties

Appearance: off-white crystals
Molecular weight: 306.39
CAS number: 94367-34-7, 94367-35-8 (trifluoroacetate)
Molecular formula: C15H18N2O3S
Solubility: Soluble in DMF, DMSO, acetonitrile, ethyl acetate. Slightly soluble in chloroform. Insoluble in water, diethyl ether
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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