sulfo-Cyanine3 DBCO
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
113F0 | 1 mg | $125 | in stock | |
213F0 | 5 mg | $325 | in stock | |
413F0 | 25 mg | $850 | in stock | |
513F0 | 50 mg | $1490 | in stock | |
613F0 | 100 mg | $1990 | in stock |
sulfo-Cyanine3 DBCO is a water-soluble fluorescent dye with cycloalkyne group for copper-free click chemistry.
DBCO (dibenzocyclooctyne) is a cyclooctyne with very high reactivity towards azides, still possessing good stability.
Absorption and emission spectra of sulfo-Cyanine3
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Alkyne functionalized, water soluble far red/near infrared emitting fluorophore sulfo-Cyanine5.5.DBCO-STP ester
Activated ester for modification of proteins/antibodies/peptides followed by introduction into copper-free click chemistry reaction.
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AF 488 DBCO
Dibenzocyclooctyne (DBCO, ADIBO) containing the green fluorophore AF 488 for labeling azide-tagged biomolecules inside live cells, whole organisms, and inanimate samples. Pure 5-isomer.General properties
Appearance: | red solid |
Mass spec M+ increment: | 916.4 |
Molecular weight: | 955.23 |
Molecular formula: | C51H55N4KO8S2 |
Solubility: | soluble in water (0.11 M = 11 g/L), DMF, DMSO |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 548 |
ε, L⋅mol−1⋅cm−1: | 162000 |
Emission maximum, nm: | 563 |
Fluorescence quantum yield: | 0.1 |
Product citations
- Michielsen, C. M. S.; van Aalen, E. A.; Merkx, M. Ratiometric Bioluminescent Zinc Sensor Proteins to Quantify Serum and Intracellular Free Zn2+. ACS Chem. Biol., 2022, 17(6), 1567–1576. doi: 10.1021/acschembio.2c00227
- Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
- Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5
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