sulfo-Cyanine3 maleimide
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
11380 | 1 mg | $115 | in stock | |
21380 | 5 mg | $290 | in stock | |
41380 | 25 mg | $695 | in stock | |
51380 | 50 mg | $1190 | in stock | |
61380 | 100 mg | $1990 | in stock |
sulfo-Cyanine3 maleimide is a water-soluble, thiol-reactive dye for labeling. This is an analog of Cy3® maleimide.
This product is recommended for labeling antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require organic co-solvent.
A non-sulfonated Cyanine3 maleimide is available.
Sulfo-Cyanine3 maleimide
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NIR fluorescent dye functionalized with cyclooctyne moiety for copper free click chemistry conjugation with azides.
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sulfo-Cyanine7 amine
NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.Cyanine7 hydrazide
Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.General properties
Appearance: | red powder |
Molecular weight: | 776.96 |
CAS number: | 1656990-68-9 |
Molecular formula: | C36H41KN4O9S2 |
IUPAC name: | 3H-Indolium, 2-[3-[1-[6-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-5-sulfo-, inner salt, potassium salt |
Solubility: | soluble in water (0.39 M = 30 g/L), DMF, DMSO |
Quality control: | NMR 1H, HPLC-MS (95+%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 548 |
ε, L⋅mol−1⋅cm−1: | 162000 |
Emission maximum, nm: | 563 |
Fluorescence quantum yield: | 0.1 |
CF260: | 0.03 |
CF280: | 0.06 |
Product citations
- Damm, A.; Paik, S.-J.; Sadhu, R.K.; Di-Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Lévy, D.; Bassereau, P. Mechanosensitivity of an ABC Membrane Transporter Revealed by Single Molecule FRET and Activity Measurement. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.24.577054
- Proksch, J.; Dal Colle, M. C. S.; Heinz, F.; Schmidt, R. F.; Gottwald, J.; Delbianco, M.; Keller, B. G.; Gradzielski, M.; Alexiev, U.; Koksch, B. Impact of Glycan Nature on Structure and Viscoelastic Properties of Glycopeptide Hydrogels. Journal of Peptide Science, 2024, 30(8), e3599. doi: 10.1002/psc.3599
- Moochickal Assainar, B.; Ragunathan, K.; Baldridge, R.D. Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD. Nature Communications, 2024, 15, 1340. doi: 10.1038/s41467-024-45541-3
- Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
Cy® is a trademark of GE Healthcare.
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