DiR, lipophilic tracer

Neuroscience Cell membrane Near infrared (NIR) imaging Microscopy Flow cytometry

Cat. #	Quantity	Price	Lead time
3433-1mg	1 mg	–	in stock
3433-5mg	5 mg	$129 $64	in stock (MOQ 2 pcs.)
3433-50mg	50 mg	$540	in stock

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DiR is a near-infrared fluorescent carbocyanine dye for cell membrane labeling in vivo and in vitro. DiR diffuses laterally to stain the entire cell, allowing it to be used as an anterograde and retrograde tracer of neurons. In intact tissue, the dye does not transfer from labeled to unlabeled cells, but some transfer may occur when the membrane is disrupted, for example, after sectioning. The dye is weakly fluorescent until incorporated into membranes.

DiR can be used with other tracers in multi-color studies, such as DiI or DiO and for NIR imaging.

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Absorption and emission spectra of DiR

General properties

Appearance:	violet-green sticky solid
Molecular weight:	1013.42
CAS number:	100068-60-8
Molecular formula:	C₆₃H₁₀₁IN₂
Solubility:	DMSO
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	750
ε, L⋅mol⁻¹⋅cm⁻¹:	254000
Emission maximum, nm:	775
Fluorescence quantum yield:	0.25
CF₂₆₀:	0.08
CF₂₈₀:	0.08

Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.