HPG (L-Homopropargylglycine)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 3313-25mg | 25 mg | $129 | in stock | |
| 3313-100mg | 100 mg | $249 | in stock | |
| 3313-1g | 1 g | please inquire | in stock |
L-Homopropargylglycine (HPG) is a noncanonical amino acid analog of methionine that contains a terminal alkyne moiety. HPG-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.
HPG is the cell-permeable compound randomly incorporated into synthesizing protein instead of methionine during translation. The resulting alkyne-labeled full-length proteins can be detected via copper-catalyzed click reaction with fluorescent or biotin-labeled azides and used for subsequent microscopic imaging or purification tasks.
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| Appearance: | off-white solid |
| Molecular weight: | 163.60 |
| CAS number: | 942518-19-6 |
| Molecular formula: | C6H10ClNO2 |
| Solubility: | good in water (max. 125 mg/mL) and DMSO (max. 250 mg/mL) |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product citations
- Baleva, M.V.; Piunova, U.; Chicherin, I.; Vasilev, R.; Levitskii, S.; Kamenski, P. Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells. International Journal of Molecular Sciences, 2024, 25(1), 93. doi: 10.3390/ijms25010093
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