Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)

Alkynes Glycan labeling Click chemistry
Cat. # Quantity Price Lead time
4130-5mg 5 mg $129 in stock
4130-25mg 25 mg $240 in stock
4130-100mg 100 mg $630 in stock
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The tetraacetylated N-(4-pentynoyl)-glucosamine (Ac4GlcNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GlcNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylglucosamine (GlcNAc).

The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.

Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated), 4130-5mg
Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated), 4130-5mg
Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated), 4130-5mg
Structure of Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)
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Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.

General properties

Appearance: beige powder
Molecular weight: 427.41
CAS number: 1361993-37-4
Molecular formula: C19H25NO10
IUPAC name: 2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-2-deoxy-1,3,4,6-tetra-O-acetyl-D-glucopyranose
Solubility: DMSO, DMF, DCM, THF, chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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