sulfo-Cyanine5 azide

Azides Click chemistry sulfo-Cyanine5
Cat. # Quantity Price Lead time
A3330 1 mg $125 in stock
B3330 5 mg $325 in stock
C3330 10 mg $470 in stock
D3330 25 mg $790 in stock
E3330 50 mg $1490 in stock
F3330 100 mg $2590 in stock
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Water-soluble Cyanine5 dye azide for click chemistry. Bright and photostable dye with red fluorescence. The reagent has high water solubility. Due to high solubility and hydrophilicity, the dye can be used for labeling biomolecules in native, purely aqueous conditions.

This reagent, instead of competing products, is supplied as an alkaline metal salt, not triethylammonium salt. Therefore, it is a powder that is easy to handle and dispense.

sulfo-Cyanine5 is an analog of Cy5®, a very popular fluorophore; therefore, this reagent is compatible with a wide range of standard fluorescent instrumentation such as imagers, plate readers, and microscopes.

Sulfo-Cyanine5 azide, A3330
Sulfo-Cyanine5 azide, A3330
Sulfo-Cyanine5 azide, A3330
Sulfo-Cyanine5 azide structure
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Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 absorbance and emission spectra

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sulfo-Cyanine5.5 azide

sulfo-Cyanine5.5 azide is a derivative of water-soluble far-red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper-free click chemistry with alkynes and cycloalkynes.

Hexynoic acid NHS ester

Hexynoic acid NHS ester for the labeling of biomolecules with alkyne group for copper-catalyzed click chemistry.

FAM amine, 6-isomer

Amine derivative of fluorescein (FAM) fluorophore, pure 6-isomer, for the enzymatic transamination labeling, reactions with electrophilic reagents, and reductive amination.
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General properties

Appearance: dark blue crystals
Molecular weight: 762.98
Molecular formula: C35H43N6KO7S2
Solubility: very high in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Kalinina, A.; Dhaliwal, J.; Xue, Y.; Vaculik, M.; McCambley, M.; Fong, B.C.; Cook, D.; Slack, R.S.; Lagace, D.C. Mitotic Activity and DNA Maintenance of Adult Neural Stem Cells is Regulated by Beclin1. bioRxiv, 2024, preprint. doi: 10.1101/2024.01.26.573092
  2. Lee, J.J.; Kim, H.; Park, H.; Lee, U.J.; Kim, C.; Lee, M.; Shin, Y.; Jung, J.-J.; Lee, H.-B.; Han, W.; Lee, H. Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres. Nucleic Acids Research, 2024, gkae251. doi: 10.1093/nar/gkae251
  3. Swan, J.; Szabó, Z.; Peters, J.; Kummu, O.; Kemppi, A.; Rahtu-Korpela, L.; Konzack, A.; Hakkola, J.; Pasternack, A.; Ritvos, O.; Kerkelä, R.; Magga, J. Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease. Biomedicine & Pharmacotherapy, 2024, 175, 116683. doi: 10.1016/j.biopha.2024.116683
  4. Kanaan, M.N.; Pileggi, C.A.; Karam, C.Y.; Kennedy, L.S.; Fong-McMaster, C.; Cuperlovic-Culf, M.; Harper, M.-E. Cystine/Glutamate Antiporter xCT Controls Skeletal Muscle Glutathione Redox, Bioenergetics and Differentiation. Redox Biology, 2024, 73, 103213. doi: 10.1016/j.redox.2024.103213
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Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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