Alkyne maleimide

Cat. # Quantity Price Lead time
41780 25 mg $95 in stock
51780 50 mg $175 in stock
61780 100 mg $200 in stock
Found better price? Let us know and we will propose the way forward!

Alkyne maleimide is a bifunctional linker reagent which allows to attach terminal alkyne to various thiol-containing molecules, such as proteins containing cysteine residues. The alkyne moiety can be then conjugated with various azides via copper-catalyzed сlick chemistry reaction.

Customers also purchased with this product

Alkyne-PEG3-maleimide

Bifunctional spacer with alkyne and maleimide groups for conjugation of biomolecules.

LumiMount® Fluorescence Mounting Medium

An aqueous anti-fade mounting medium for coverslipping cells and tissues stained with various fluorescent dyes.

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

General properties

Appearance: colorless solid
Mass spec M+ increment: 234.1
Molecular weight: 234.25
Molecular formula: C12H14N2O3
Solubility: good in DMSO, DMF, alcohols, limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Hulce, K.R.; Jaishankar, P.; Lee, G.M.; Bohn, M.-F.; Connelly, E.J.; Wucherer, K.; Ongpipattanakul, C.; Volk, R.F.; Chuo, S.-W.; Arkin, M.R.; Renslo, A.R.; Craik, C.S. Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine. Cell Chemical Biology, 2022, 29(5), 785-798.e19. doi: 10.1016/j.chembiol.2022.03.007
  2. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.