Azidobutyric acid NHS ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
53720 | 50 mg | $110 | in stock | |
63720 | 100 mg | $210 | in stock | |
73720 | 1 g | $950 | in stock | |
83720 | 5 g | please inquire | in stock |
Convert your proteins and peptides into click chemistry reactive form with this reagent.
While click chemistry involves reaction between terminal alkyne and azide, both azides and alkynes are very uncommon in nature. However, there are reagents to attach these fragments to abundant amino groups which are ubiquitous in the world of biomolecules. This azido-NHS ester is designed for the conversion of proteins, peptides, amino-DNA, and other amines into click chemistry reactive azides.
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TAMRA NHS ester, 5-isomer
Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides. Pure 5-isomer.ROX NHS ester, 6-isomer
Pure 6-isomer of ROX (Rhodamine X, R101) NHS-ester for amine labeling.AmdU (5-Azidomethyl-2'-deoxyuridine)
Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.General properties
Appearance: | colorless solid |
Mass spec M+ increment: | 111.0 |
Molecular weight: | 226.19 |
CAS number: | 943858-70-6 |
Molecular formula: | C8H10N4O4 |
IUPAC name: | Butanoic acid, 4-azido-, 2,5-dioxo-1-pyrrolidinyl ester |
Solubility: | soluble in organic solvents (DMF, DMSO) |
Quality control: | NMR 1H (95%), HPLC |
Storage conditions: | Storage: 12 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | Download |
Product specifications |
Product citations
- Osuofa, J.; Husson, S.M. Preparation of Protein A Membranes Using Propargyl Methacrylate-Based Copolymers and Copper-Catalyzed Alkyne–Azide Click Chemistry. Polymers, 2024, 16(2), 239. doi: 10.3390/polym16020239
- Skardžiūtė, K.; Kvederavičiūtė, K.; Pečiulienė, I.; Narmontė, M.; Gibas, P.; Ličytė, J.; Klimašauskas, S.; Kriukienė, E. One-pot trimodal mapping of unmethylated, hydroxymethylated, and open chromatin sites unveils distinctive 5hmC roles at dynamic chromatin loci. Cell Chemical Biology, 2024, 31(3), 607-621.e9. doi: 10.1016/j.chembiol.2023.12.003
- Afting, C.; Walther, T.; Drozdowski, O. M.; Schlagheck, C.; Schwarz, U. S.; Wittbrodt, J.; Göpfrich, K. DNA Microbeads for Spatio-Temporally Controlled Morphogen Release within Organoids. Nat. Nanotechnol., 2024, 1-9. doi: 10.1038/s41565-024-01779-y
- Sim, J.; Li, M.; Park, K. M.; Kim, K. Identification of Mitochondrial Proteins Associated with Cyanine 5 Using a Combination of Affinity-Based Photocrosslinking with Bio-Orthogonal Supramolecular Latching. J. Porphyrins Phthalocyanines, 2023, 27(07n10), 1148–1155. doi: 10.1142/S108842462350058X
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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