Azide-PEG3-carboxylic acid
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 2558-1g | 1 g | $265 | in stock | |
| 2558-5g | 5 g |
$950
|
in stock |
Azide-PEG3-carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups.
This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.
The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (сlick сhemistry reactions), and the carboxyl group can be activated and react with various amines.
The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.
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DBCO amine trifluoroacetate
Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.General properties
| Appearance: | colorless liquid |
| Molecular weight: | 247.25 |
| CAS number: | 1056024-94-2 |
| Molecular formula: | C9H17N3O5 |
| IUPAC name: | 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid |
| Solubility: | good in water and most organic solvents |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. |
| MSDS: | Download |
| Product specifications |
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