CytoTracer® Orange CMTMR
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 4276-50ug | 50 ug |
$22.00
|
in stock |
CytoTracer® Orange CMTMR is a fluorescent orange probe designed to label viable cells and track them over extended periods. At recommended working concentrations, it displays low cytotoxicity and exerts negligible effects on cell proliferation rates or overall cellular physiology. The reagent is suitable for assessing cell proliferation, viability, spatial localization, and migratory behavior in both in vivo and in vitro experiments.
This cell-permeable stain undergoes intracellular conversion to membrane-impermeable product. Upon division, the label is passed exclusively to daughter cells without transferring to neighboring cells, and the fluorescence remains detectable for at least 72 hours, typically persisting through three to six population doublings.
The compound features a chloromethyl group that reacts with intracellular thiol-containing components via a glutathione S-transferase-dependent mechanism. This property ensures that the dye is retained within cells even after fixation and permeabilization, making it compatible with subsequent immunofluorescence staining.
Excitation and emission spectra of CytoTracer Orange CMTMR
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General properties
| Appearance: | red solid |
| Molecular weight: | 554.0 |
| CAS number: | 323192-14-9 |
| Molecular formula: | C32H28ClN3O4 |
| IUPAC name: | 9-[2-carboxy-4(or 5)-[[4-(chloromethyl)benzoyl]amino]phenyl]-3,6-bis(dimethylamino)-xanthylium, inner salt |
| Quality control: | NMR 1H and HPLC-MS (85+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 540 |
| Emission maximum, nm: | 565 |
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