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LumiTracker ER Green (also known as ER-Tracker™ Green) is a cell-permeant, highly selective for the endoplasmic reticulum (ER) stain for live cell imaging. LumiTracker ER Green is a derivative of green-fluorescent BDP FL dye coupled with Glibenclamide (Glyburide). Glibenclamide binds to the sulphonylurea (SUR) receptors of ATP-sensitive potassium channels (KATP), which are prominent on the endoplasmic reticulum. The staining is partially retained after fixation with formaldehyde. LumiTracker ER Green is not suitable for staining cells after fixation.
Note that the pharmacological activity of glibenclamide could potentially affect ER function. Variable expression of sulphonylurea receptors in some specialized cell types may result in non-ER labeling.
ER-Tracker™ is the trademark of Molecular Probes Inc.
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.