sulfo-Cyanine5 alkyne

Alkynes Click chemistry sulfo-Cyanine5
Cat. # Quantity Price Lead time
A33B0 1 mg $125 in stock
B33B0 5 mg $290 in stock
C33B0 10 mg $470 in stock
D33B0 25 mg $850 in stock
E33B0 50 mg $1490 in stock
F33B0 100 mg $1990 in stock
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Water soluble reagent with alkyne group for click chemistry. Sulfo-Cyanine5 is a sulfonated dye with high hydrophilicity and aqueous solubility, exceptionally high extinction coefficient, good quantum yield, and compatibility with many instruments.

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

sulfo-Cyanine5 alkyne, F33B0
sulfo-Cyanine5 alkyne, F33B0
sulfo-Cyanine5 alkyne, F33B0
Structure of Sulfo-Cyanine5 alkyne
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Absorbance and emission spectra of sulfo-Cyanine5

Absorbance and emission spectra of sulfo-Cyanine5

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Alkyne derivative of TAMRA dye, pure 5-isomer for сopper-catalyzed сlick chemistry.

General properties

Appearance: dark blue solid
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Product citations

  1. Yoshikawa, A. M.; Rangel, A. E.; Zheng, L.; Wan, L.; Hein, L. A.; Hariri, A. A.; Eisenstein, M.; Soh, H. T. A Massively Parallel Screening Platform for Converting Aptamers into Molecular Switches. Nat Commun, 2023, 14(1), 2336. doi: 10.1038/s41467-023-38105-4
  2. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
  3. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  4. Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
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Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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