Alkyne CPG 1000A

Cat. # Quantity Price Lead time
15860 100 mg $60 in stock
25860 250 mg $120 in stock
35860 500 mg $230 in stock
45860 1 g $380 in stock
55860 5 g $1450 in stock
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Controlled pore glass solid support for the synthesis of 3'-alkyne modified oligonucleotides. The support allows to prepare oligos of up to 100mer.

The modification is stable in standard deblocking conditions, and can tolerate ammonia, AMA, and other basic reagents.

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THPTA ligand

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General properties

Appearance: white beads
MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 1000
Typical loading, umol/g: 40−70
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature

Product citations

  1. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
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