DBCO-amine trifluoroacetate

Cycloalkynes Copper-free click chemistry Crosslinking Amines

Cat. #	Quantity	Price	Lead time
1280-100mg	100 mg	$218	in stock
1280-500mg	500 mg	$678	in stock
1280-1g	1 g	$1200 $1018	in stock

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Items in stock will be shipped on 05/19/2025

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Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.

Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain-promoted alkyne azide cycloaddition (SPAAC) – a copper-free click chemistry reaction. DBCO reacts instantly with azides. The reaction rate is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines.

Structure of DBCO-amine trifluoroacetate

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General properties

Appearance:	beige to brawn solid
Molecular weight:	432.44
Molecular formula:	C₂₃H₂₃F₃N₂O₃
Solubility:	good in DMF, DMSO, DCM
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.