Pyrene azide 1
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A1530 | 1 mg | $110 | 5 days | |
| B1530 | 5 mg | $210 | in stock | |
| C1530 | 10 mg | $310 | in stock | |
| D1530 | 25 mg |
$410
|
in stock | |
| E1530 | 50 mg |
$695
|
in stock |
This product will be discontinued soon in favor of Pyrene azide 2
Pyrene is a polyaromatic hydrocarbon with strong short-wavelength fluorescence. Unlike other fluorescent dyes, polyaromatic hydrocarbons are fluorescent probes with a strong sensitivity to the microenvironment. Thus, its fluorescence is different in polar, and nonpolar environments. Other effects can also be observed.
When two pyrenes are in close proximity, they form excimers. Excimer formation can be easily observed, and quantitatively estimated using fluorescent spectra.
Pyrene azide is a reagent for easy pyrene click chemistry labeling of any alkyne-bearing molecule. It allows turning any molecule into a pyrene-bearing probe.
This azide contains a hydrophilic triethyleneglycol linker to mitigate intrinsic pyrene hydrophobicity and facilitate attachment to biomolecules in aqueous solutions.
Another pyrene azide for click chemistry labeling is also available: Pyrene azide 2.
Absorption and emission spectra of pyrene fluorophore
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TR azide, 5-isomer
Azide derivative of red fluorescent dye TR for сlick сhemistry conjugation. Pure 5-isomer.AF 343 (Coumarin)-X-azide
AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.3-Ethynylperylene
Alkyne derivative of ultra-bright and photostable perylene fluorophore.General properties
| Appearance: | off-white to yellowish solid |
| Molecular weight: | 402.45 |
| CAS number: | 2135330-58-2 |
| Molecular formula: | C23H22N4O3 |
| Solubility: | soluble in dichloromethane, chloroform, moderately soluble in DMSO, DMF, acetonitrile |
| Quality control: | NMR 1H (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 343; 326; 313; 276; 265; 242; 234 |
| Emission maximum, nm: | 377; 397 |
Product citations
- Semikolenova, O.; Sakovina, L.; Akhmetova, E.; Kim, D.; Vokhtantsev, I.; Golyshev, V.; Vorobyeva, M.; Novopashin, S.; Novopashina, D. Photoactivatable nanoCRISPR/Cas9 System Based on crRNA Reversibly Immobilized on Carbon Nanoparticles. International Journal of Molecular Sciences, 2021, 22(20), 10919. doi: 10.3390/ijms222010919
- Krasheninina, O.A.; Fishman, V.S.; Lomzov, A.A.; Ustinov, A.V.; Venyaminova, A.G. Postsynthetic On-Column 2′ Functionalization of RNA by Convenient Versatile Method. International Journal of Molecular Sciences, 2020, 21(14), 5127. doi: 10.3390/ijms21145127
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