Azide-PEG4-carboxylic acid
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 2723-250mg | 250 mg | $134 | 21 days | |
| 2723-1g | 1 g | $299 | 21 days |
Azide-PEG4-carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups. This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.
The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (сlick сhemistry reactions), and the carboxyl group can be activated and react with various amines.
The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.
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A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).General properties
| Appearance: | yellowy liquid |
| Molecular weight: | 291.30 |
| CAS number: | 1257063-35-6 |
| Molecular formula: | C11H21N3O6 |
| IUPAC name: | 15-azido-4,7,10,13-tetraoxapentadecanoic acid |
| Solubility: | good in water and most organic solvents |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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