Azide-PEG4-carboxylic acid

Azides Carboxylic acids Crosslinking
Cat. # Quantity Price Lead time
2723-250mg 250 mg $134 21 days
2723-1g 1 g $299 21 days
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Azide-PEG4-carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups. This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.

The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (сlick сhemistry reactions), and the carboxyl group can be activated and react with various amines.

The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.

Structure of Azide-PEG4-carboxylic acid
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General properties

Appearance: yellowy liquid
Molecular weight: 291.30
CAS number: 1257063-35-6
Molecular formula: C11H21N3O6
IUPAC name: 15-azido-4,7,10,13-tetraoxapentadecanoic acid
Solubility: good in water and most organic solvents
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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