HPG (L-Homopropargylglycine)

Cat. # Quantity Price Lead time
3313-25mg 25 mg $99 in stock
3313-100mg 100 mg $229 in stock
3313-1g 1 g please inquire in stock
Found better price? Let us know and we will propose the way forward!

L-Homopropargylglycine (HPG) is a noncanonical amino acid analog of methionine that contains a terminal alkyne moiety. HPG-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.

HPG is the cell-permeable compound randomly incorporated into synthesizing protein instead of methionine during translation. The resulting alkyne-labeled full-length proteins can be detected via copper-catalyzed click reaction with fluorescent or biotin-labeled azides and used for subsequent microscopic imaging or purification tasks.

Customers also purchased with this product

AF 488 azide

AF 488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF 488 streptavidin

AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.

General properties

Appearance: off-white solid
Molecular weight: 163.60
CAS number: 942518-19-6
Molecular formula: C6H10ClNO2
Solubility: good in water, DMSO
Quality control: NMR 1H and GCMS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Product citations

  1. Baleva, M.V.; Piunova, U.; Chicherin, I.; Vasilev, R.; Levitskii, S.; Kamenski, P. Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells. International Journal of Molecular Sciences, 2024, 25(1), 93. doi: 10.3390/ijms25010093
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.