F-ara-EdU (2′-Deoxy-2′-fluoro-5-ethynyluridine)

Cat. # Quantity Price Lead time
3438-5mg 5 mg
– 
in stock
3438-25mg 25 mg
$375
in stock
3438-100mg 100 mg
$825
in stock
3438-500mg 500 mg
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F-ara-EdU (2′-deoxy-2′-fluoro-5-ethynyluridine) is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU (5-Bromo-2′-deoxyuridine) and EdU (5-Ethynyl-2′-deoxyuridine).

F-ara-EdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. Metabolic incorporation of F-ara-EdU into DNA can be detected by copper-catalyzed click reaction with fluorescent or biotin-labeled azides.

In contrast to EdU, F-ara-EdU causes little or no cellular arrest or DNA synthesis inhibition. Therefore, F-ara-EdU is ideally suited for pulse-chase experiments aimed at birth-dating DNA in vivo and long-term cell survival estimation.

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General properties

Appearance: off-white powder
Molecular weight: 270.22
CAS number: 95740-26-4
Molecular formula: C11H11FN2O5
Solubility: in water, DMSO, DMF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
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