F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 3438-5mg | 5 mg | – | in stock | |
| 3438-25mg | 25 mg | $375 | in stock | |
| 3438-100mg | 100 mg |
$825
|
in stock | |
| 3438-500mg | 500 mg | please inquire | in stock |
F-ara-EdU (2’-deoxy-2’-fluoro-5-ethynyluridine) is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU (5-Bromo-2’-deoxyuridine) and EdU (5-Ethynyl-2’-deoxyuridine).
F-ara-EdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. Metabolic incorporation of F-ara-EdU into DNA can be detected by copper-catalyzed click reaction with fluorescent or biotin-labeled azides.
In contrast to EdU, F-ara-EdU causes little or no cellular arrest or DNA synthesis inhibition. Therefore, F-ara-EdU is ideally suited for pulse-chase experiments aimed at birth-dating DNA in vivo and long-term cell survival estimation.
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Biotin-11-dUTP
Biotin-labeled deoxyuridine triphosphate for enzymatic incorporation into DNA and indirect detection.Copper(II)-TBTA complex
A catalyst for click reaction. A stable copper(II) complex which must be converted to monovalent copper(I) in situ using reducing agents. The complex can be used to prepare a reaction buffer of any composition.FCCP, ATPase inhibitor
FCCP is a strong uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP production by transporting protons across cellular membranes.General properties
| Appearance: | off-white powder |
| Molecular weight: | 270.22 |
| CAS number: | 95740-26-4 |
| Molecular formula: | C11H11FN2O5 |
| Solubility: | in water, DMSO, DMF |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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