F-ara-EdU (2′-Deoxy-2′-fluoro-5-ethynyluridine)

Alkynes Cell proliferation Click chemistry
Cat. # Quantity Price Lead time
3438-5mg 5 mg
– 
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3438-25mg 25 mg
$375
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3438-100mg 100 mg
$825
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3438-500mg 500 mg
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F-ara-EdU (2′-deoxy-2′-fluoro-5-ethynyluridine) is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU (5-Bromo-2′-deoxyuridine) and EdU (5-Ethynyl-2′-deoxyuridine).

F-ara-EdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. Metabolic incorporation of F-ara-EdU into DNA can be detected by copper-catalyzed click reaction with fluorescent or biotin-labeled azides.

In contrast to EdU, F-ara-EdU causes little or no cellular arrest or DNA synthesis inhibition. Therefore, F-ara-EdU is ideally suited for pulse-chase experiments aimed at birth-dating DNA in vivo and long-term cell survival estimation.

F-ara-EdU ((2’S)-2’-Deoxy-2’-fluoro-5-ethynyluridine), 3438-500mg
F-ara-EdU ((2’S)-2’-Deoxy-2’-fluoro-5-ethynyluridine), 3438-500mg
F-ara-EdU ((2’S)-2’-Deoxy-2’-fluoro-5-ethynyluridine), 3438-500mg
Structure of F-ara-EdU ((2’S)-2’-Deoxy-2’-fluoro-5-ethynyluridine)
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General properties

Appearance: off-white powder
Molecular weight: 270.22
CAS number: 95740-26-4
Molecular formula: C11H11FN2O5
Solubility: in water, DMSO, DMF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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